Synthesis and Characterization of Drug-Enzyme Conjugates

  • Saeed-ul-Hassan, S. (Faculty of Pharmacy, University of the Punjab, (Allama Iqbal Campus)) ;
  • Rowell, Frederick J. (Institute of Pharmacy University of Sunderland)
  • Published : 2000.12.01

Abstract

Two drug-enzyme conjugates of dexamethasone-subtilisin and dexamethasone-cellulase have been synthesized and characterized to study their drug-protein incorporation ratio, immunoreactivity, enzyme activity and stability and these studies proved that a variety of drug enzyme conjugates could also be synthesized and characterized.

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