중추성 작용 약물의 뇌파 효과의 정량화를 위한 스펙트럼 분석에 필요한 기본적 조건의 검토

Basic ]Requirements for Spectrum Analysis of Electroencephalographic Effects of Central Acting Drugs

We intended to show some basic requirements for spectrum analysis of electroencephalogram (EEG) by visualizing the differences of the results according to different values of some parameters for analysis. Spectrum analysis is the most popular technique applied for the quantitative analysis of the electroen- cephalographic signals. Each step from signal acquisition through spectrum analysis to presentation of parameters was examined with providing some different values of parameters. The steps are:(1) signal acquisition; (2) spectrum analysis; (3) parameter extractions; and (4) presentation of results. In the step of signal acquisition, filtering and amplification of signal should be considered and sampling rate for analog-to-digital conversion is two-time faster than highest frequency component of signal. For the spectrum analysis, the length of signal or epoch size transformed to a function on frequency domain by courier transform is important. Win dowing method applied for the pre-processing before the analysis should be considered for reducing leakage problem. In the step of parameter extraction, data reduction has to be considered so that statistical comparison can be used in appropriate number of parameters. Generally, the log of power of all bands is derived from the spectrum. For good visualization and quantitative evaluation of time course of the parameters are presented in chronospectrogram.