Biomolecules & Therapeutics
- 제8권1호
- /
- Pages.38-43
- /
- 2000
- /
- 1976-9148(pISSN)
- /
- 2005-4483(eISSN)
Sprague-Dawley계 정상 흰쥐에서 위점막 알코올 탈수소효소 활성에 대한 성별의 영향
The Effect of Gender on the Gastric Alcohol Dehydrogenase (GADH) Activity in Normal Sprague-Dawley Rats
초록
Several studies have shown that the stomach has sufficient alcohol dehydrogenase (ADH) activity to metabolize some amount of orally administered alcohol and the sex-related differences in the first-pass metabolism of alcohol might be associated with differences in the activity of gastric ADH(GADH). The aim of this study was to asses the sex-related differences in GADH in 48 male and 48 female Sprague-Dawley rats aged 1, 4, 10, 15, 20, and 30 weeks which each aged group had same sex ratio. The GADH activity was determined spectrophotometrically at 37
키워드