Microbiology and Biotechnology Letters (한국미생물·생명공학회지)

The Korean Society for Microbiology and Biotechnology (한국미생물·생명공학회)
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On-line Analysis of Phellinus linteus WI-001 Fermentation Parameters.

Phellinus linteus WI-001 발효에 배양공정 parameter의 온라인 분석

  • 김종래 (환인제약(주) 중앙연구소,강원대학교 자연과학대학 생명과학부) ;
  • 권호균 (환인제약(주)중앙연구소) ;
  • 전계택 (강원대학교 자연과학대학 생명과학부) ;
  • 이계관 (환인제약(주)중앙연구소)
  • Published : 2000.10.01
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Abstract

Fermentation parameters were estimated by use of a vent gas analyzer coupled to a computer data acquisition system in cultivation of Phellinus linteus WI-001, pro-ducer of polysaccharides known to have potent anticancer activities. Oxygen uptake rate(OUR), a critical indicator of the cells activities, was calculated by applying oxygen mass balance. In addition, by dividing the oxygen uptake rate hy the total oxygen consumed, on-line estimation of the cells specific growth rate was successfully done. It was also possible to estimate cell concentration directly bt use of oxygen-cell yield($Y_{x/o}$ ) which was obtained based on a correlation between cell growth and total oxygen consumed.

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References

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