Journal of Nutrition and Health

  • 제33권3호
  • /
  • Pages.296-303
  • /
  • 2000
  • /
  • 2288-3886(pISSN)
  • /
  • 2288-3959(eISSN)
한국영양학회 (The Korean Nutrition Society)
권호 표지

가임기 여성의 엽산 섭취량 및 엽산영양상태

Dietary Intakes and Status of Folate in Koean Women of Child-bearing Potential

  • 임현숙 (전남대학교 가정대학 식품영양학과)
  • 발행 : 2000.04.01
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

We examined the folate intakes and assessed folate nutritional status of Korean women with childbearing potential. A total of 91 healthy women aged between 15 and 49 participated. They were divided into three groups by their age : A(15-24 yrs), B(25-34 yrs) and C(35-49 yrs). Folate intakes were determined by direct analysis. The foods consumed for 24 hours were collected proportionally and assessed folate. Their blood drawn in fasting state were analyzed folate levels. Folate contents of food homogenate, plasma and erythrocyte were determined a microbiological method using Lactobacillus. casei (ATCC 7469). Prior to the micro-assay, the food homogenate were treated with alpha-amylase, protease and folate conjugase. Mean daily folate intake of the total subjects was 145.8$\mu\textrm{g}$/d and in each group of A, B, and C was 114.0$\mu\textrm{g}$/d, 141.6$\mu\textrm{g}$/d, and 164.6$\mu\textrm{g}$/d, respectively. That of group C was significantly higher than that of group A(p<0.05). However, those of all the groups were lower than compared to the Korean Recommened Dietary Allowances(RDA) for folate. Especially the subjects in the group A consumed folate least that was below the half of the Korean RDA. The mean energy intake of all subjects was 1638㎉/d and those in each group of A, B, and C did not meet the Korean RDA for energy. The energy intake were significantly correlated with folate intakes(r=0.5050, p<0.001). Mean plasma and erythrocyte folate concentrations of total subjects were 6.9ng/mL and 266.3ng/mL, respectively. None were found to be deficient both in plasma(<3ng/mL)and erythrocyte (<140ng/mL) folate levels. There was only one subject who had red blood cell folate level below 157ng/mL concentration. These results show that folate status of the Korean women of reproductive age is not much bad. But it should be better that letting them improve their folate status by increasing energy intake, choosing high folate foods.

키워드

참고문헌

  1. Br J Obstet Gynaecol v.100 Folate and fetal development Hibbard BM
  2. Dietary reference intakes for thiamin, riboflabin, niacin,vitamin $B_6$, folate, vitamin $B_{12}$, pantothenic acid, biotin, and choline Institute of Medcine
  3. Obstet Gynecol v.67 Unplanned pregnancies in the US Grimes DA
  4. MMWR v.41 Recommendations for the use of folic acid to reduce number of cases of spina bifida and other neural tube defects Public Health Service
  5. Am J Clin Nutr v.50 Folate intake and food sources in the US population Subar AF;Block G;James LD
  6. Nationwide Food Consumer Continuing Survey of Food Intakes by Individuals. Women 19-50 years and their children 1-5 years US Dept of Agriculture
  7. Dietary intake of vitamins, minerals, and fiber of persons ages 2 months and over in the United States: Third National Health and Nutrition Examination Survey, Phase 1, 1988-1991, Advanced data from vital and health statistics Alimo K;McDowell MA;Briefel RR;Bischef AM;Caughman CR
  8. Federal Resister v.61 Food Standards: amendment of standards identity for enriched grain products to require addition of folic acid Food and Drug Administration
  9. J Am Diet Assoc v.96 What partitioners need to know about folic acid Hine RJ
  10. Requirements of Vitamin A, Iron, Folate Vitamin B12. Report of Joint FAO/WHO Expert Consultation FAO
  11. Am J Clin Nutr v.46 Folate requirement and metabolism in nonpregnant women Sauberlich HE;Kretsch MJ;Skala JH;Johnson HL;Taylor PC
  12. Korean J Nutrition v.26 Serum folate and iron levels of pregnant, lactating and non-pregnant, non-lactating women Chang N;Kang M;Paik HY;Kim IH;Cho YW;Paik SC;Shin YW
  13. Korean J Nutrition v.32 Dietary folate intake Korean women of childbearing age Kim Y;Kim K;Chang N
  14. Korean J Nutrition v.26 Effect of dietary folate intakes on serum folate levels of pregnant and lactating women Kang M;Chang N
  15. Korean J Community Nutrition v.4 Blood folate level determined by a microplate reader and folate intake measured by a weighted food record Hyun TS;Han YH;Lim YH
  16. Recommended Dietary Allowances for Koreans(6th revision) The Korean Nutrition Society
  17. Food Composition Table(5th revision) National Rural Living Science Institute
  18. Korean J Nutr v.10 The measurement of folacin content in Korean foods Part 1. folate distribution in vegetables Kim YM
  19. Korean J Nutr v.10 The measurement of folacin content in Korean foods Part 2. folate distribution in fruits Kim YM
  20. Korean J Nutr v.12 The measurement of folacin content in Korean foods Part 3. folate distribution in various foods Kim YM
  21. J Agri Food Sci v.45 Food folate assay with protease, α-amylase, and folate conjugase treatment Tamura T;Mizuno Y;Johnston KE;Jacob RA
  22. J Agri Food Chem v.45 Determination of folate in cerealgrain food products using trienzyme extraction and combined affinity and reversed-phase liquid chromatography Pfeiffer CM;Rogers LM;Gregory JF
  23. Food Chem v.63 Measurable human milk folate is increased by treatment with α-amylase and protease in addition to folate conjugase Lim HS;Mackey AD;Tamura T;Wong SC;Picciano MF
  24. National Health Survey Korean Institute for Health and Social Affairs
  25. Folic Acid Metabolism in Health and Disease Microbiological assay of folate Tamura T;MF Picciano;ELR Stokstad;JF Gregory III(eds.)
  26. Eur J Clin Nutr v.51 no.Suppl 3 Folate intake and status among adults in the Netherlands Brussaard JH;Lowik MR;van den Berg H;Brants HA;Goldbohm RA
  27. Eur J Obstet Gynecol Report Biol v.70 Folate intake in young women and their knowledge of preconceptional folate supplementation to prevent neural tube defects Wild J;Schorah CJ;Mande K;Levene MI
  28. J Am Med Assoc v.277 Predictors of red blood cell folate level in women attempting pregnancy Brown JE;Jacobs DR;Hartman TJ;Barosso GM;Atang JS;Gross MD;Zeuke MA
  29. Korean J community Nutrition v.4 A study on sodium and potassium balance of college women in Seoul Lee YK;Sung CJ;Choi MK
  30. J Korean Soc Dietary Culture v.9 A study on nutritional status and one serving size of commonly consumed dish in Korean college women Kim MK;Lee JY
  31. J Am Diet Assoc v.84 Food frequency related to folacin status in adolescents Bailey LB;Wagner PA;Davis CG;Dinning JS
  32. Am J Clin Nutr v.46 Folacin status in adolescent females Clark AJ;Mossholder S;Gates R