생명과학회지 (Journal of Life Science)

  • 제10권5호
  • /
  • Pages.467-474
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  • 2000
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  • 1225-9918(pISSN)
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  • 2287-3406(eISSN)
한국생명과학회 (Korean Society of Life Science)
권호 표지

옻나무 수피 추출물이 마우스의 지질농도 및 지질과산화에 미치는 영향

Effect of Water Extract from Stem Bark of Rhus verniciflua Stokes on the Concentrations of Lipid and Lipid Peroxidation in Mice

  • 차재영 (동아대학교 생명자원과학부) ;
  • 조영수 (동아대학교 생명자원과학부)
  • 발행 : 2000.10.01
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초록

Male mice (ddY strain) were fed a laboratory chow diet containing the water extract from stem bark of Rhus verniciflua Stokes (RVS) for 14 days. There were no significant difference in body weight gain, feed intake, the hepatic lipid profile and serum total cholesterol and phodpholipid concentrations. The concentration of triglyceride in serum was significantly lower in the RVS group than that in the control group. The concentration of high-density-lipoprotein cholestrol in serum was significantly higher in the RVS group than that in the control group. The methanol extract from RVS stem bark effectively inhibited the formation of thiobarbituric acid-reactive substances as a marker of lipid peroxidation of liver microsomes in a concentration-dependent manner. This study showed that the water extract from stem bark of RVS decreased the serum triglyceride concentration and methanol extract has an antioxidative activity.

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