Journal of Life Science (생명과학회지)

Korean Society of Life Science (한국생명과학회)
권호 표지

Effect of Water Extract from Stem Bark of Rhus verniciflua Stokes on the Concentrations of Lipid and Lipid Peroxidation in Mice

옻나무 수피 추출물이 마우스의 지질농도 및 지질과산화에 미치는 영향

  • 차재영 (동아대학교 생명자원과학부) ;
  • 조영수 (동아대학교 생명자원과학부)
  • Published : 2000.10.01
Download PDF
⟨ Previous Next ⟩

Abstract

Male mice (ddY strain) were fed a laboratory chow diet containing the water extract from stem bark of Rhus verniciflua Stokes (RVS) for 14 days. There were no significant difference in body weight gain, feed intake, the hepatic lipid profile and serum total cholesterol and phodpholipid concentrations. The concentration of triglyceride in serum was significantly lower in the RVS group than that in the control group. The concentration of high-density-lipoprotein cholestrol in serum was significantly higher in the RVS group than that in the control group. The methanol extract from RVS stem bark effectively inhibited the formation of thiobarbituric acid-reactive substances as a marker of lipid peroxidation of liver microsomes in a concentration-dependent manner. This study showed that the water extract from stem bark of RVS decreased the serum triglyceride concentration and methanol extract has an antioxidative activity.

Keywords

References

  1. Free Rad. Biol. Med. v.10 Oxygen free radicals and Parkinso's disease. Adams,Jr.J. D.;Odunze, I. N.
  2. Proc. Natl. Acad. Sci. USA v.85 Oxidative stress to DNA : relation species metabolic rate and life span. Adelman, R.;R. L. Saul;B. N. Ames
  3. Am. J. Cardiol. v.70 Relation of HDL-cholesterol and triglycerides to incidence of atherosclertic coronary heart disease (The PROCAM Experimence). Assmann, G.;H. Schulth
  4. J. Biol. Chem. v.234 Colorimetric assay methods for free and phosphorylated glyceric acids. Bartlett, G. R.
  5. Microsomal lipid peroxidation. In "Methods in Enzymology" v.52 Buege, J. A.;S. D. Aust;Gleischer, S.(ed.);parker, L.(ed.)
  6. J. Korean Soc. Food Sci. Nutr. v.29 Effect of water-soluble extract from leaves of Morus alba and Cudrania tricuspidata on the lipid peroxidation in tissues of rats. Cha, J. Y.;H. J. Kim;Y. S. Cho
  7. J. Korean Soc. Food Sci. Nutr. v.28 Antioxidative activities and contents of polyphenolic compound of Cudrania tricuspidata. Cha, J. Y.;H. J. Kim;C. H. Chung;Y. S. Cho
  8. J. Korean Soc. Food Sci. Nutr. v.29 Effect of potato polyphenolics on hyperlipidemia in rats. Cha, J. Y.;Y. S. Cho
  9. Agric. Chem. Biotechnol. v.43 Effect of water extract of leaves from Morus alba and Cudrania tricuspidata on the lipid concentration of serum and liver in rats. Cha, J. Y.;H. J. Kim;B. S. Jun;Y. S. Cho
  10. Korean J. Life Science. v.9 Effect of hesperetin and naringenin on lipid concentration in orotic acid treated mice. Cha, J. Y.;S. Y. Kim;S. J. Jeong;Y. S. Cho
  11. J. Natl. Produc. v.54 Antilhyperlipidemic effects of flavonoids from Prunus Davidiana Choi, J. S.;T. Yokozawa;H. Oura
  12. J. Korean Soc. Food Nutr. v.25 Feeding effect of oriental medicine on the functional properties of pig meat. Choi,J. H.;D. W. Kim;Y. S. Moon;D. S. Chung
  13. Clin. Chim. Acta. v.22 A colorimetric method for estimating serum triglyceride. Fletcher, M. J.
  14. J. Biol. Chem. v.226 A simple method for the isolation and purification of total lipids from animal tissues. Folch, J.;M. Lees;G. H. Sloane-Starley
  15. Medicine (Baltimore) v.60 Hyperlipidemia and coronary athersclerosis. Inkeles, S.;D. Eisenberg
  16. Biochem. Biophys. Acta. v.1085 Cholesterol transport between cells and high density lipoprotein. Johnson, W. J.;F. H. Mahlberg;G. H. Rothblat;M. C. Phillps
  17. J. Invest. Dermatol. v.108 Moldulation of fatty acid oxidation alters contact hypersensitivity to urushiols : role of aliphatic chain beta-oxidation in processing and activation of urushiols. Kalergis, A. M.;C. B. Lopez;M. I. Becker;M. I. Diaz; J. Sein;J. A. Garbarino;A. E. De Ioannes
  18. Korean J. Life Science. v.9 Effects of Citus flavonoid, hesperidin and naringin on lipid metabolism in HepG2 cells. Kim, B. K.;J. Y. Cha;Y. S. Cho
  19. Korean J. Food Sci. Technol. v.31 Isolation of antioxidative compounds from the bark of Rhus verniciflua STOKES screened from some Chinese medicinal plants. Kim, I. W.;D. H. Shin;U. Choi
  20. Korean J. Food Sci. Technol. v.31 Identification of antioxidative components from dthanol extract of Rhus verniciflua STOKES. Kim, I. W.;D. H. Shin;N. I. Baek
  21. Korean J. Food Sci. Technol. v.27 Antioxidative effects of soybean extracts by using various solvents. Kim, J. Y.;Y. S. Maeng;K. Y. Lee
  22. J. Toxicol. Pub. Health. v.14 Effects of natural bioactive substances on hydroxyl radical in mouse forebrain cell culture. Lee, J. C.;K. T. Lim
  23. Korean J. Food Sci. Technol. v.25 Antioxidative effect of us javanica Linne extract by various solvents. Lee, Y. J.;D. H. Shin;Y. S. Chang;W. S. Kang
  24. J. Korean Sco. Food Nutr. v.21 Effect of dietary protein levels, caffeine and green tea on body fat deposition in wistar rats. Lee, C. H.;B. K. Choi;W. C. Lee;C. I. Park;Y. Furukawa;S. Kimura
  25. Korean J. Food Sci. Technol. v.29 Antioxidative effects of ethanol extract from Rhus verniciflua STOKES. Lim, K. T.;J. H. Shin
  26. Circulation v.85 Triglycerides and LDL-cholesterol concentrations on coronary heart disease risk in the Helsinki Heart Study, Manninen, V.;L. Tenkanen;P. Koskinen;J. K. Huttunen;M. Manntari;O. P. Heinonen;M. H. Frick.
  27. J. Nutr. Sci. Vitaminol. v.32 Effect of green tea catechins on plasma cholesterol level in cholesterol-fed rats. Muramatsu, K.;M. Fukuyo;Y. Hara
  28. J. Ethnopharmacol. v.61 Inhibitory effect of Oren-gedoku-to (Huanglian-Jie-Du-Tang) extract on hepatic triglyceride accumulation with the progression of carbon tetrachloride induced acute liver injury in rats. Ohta, Y.;E. Sasaki;K. Nishida;M. Kongo;T. Hayashi;M. Nagata;I. Ishiguro
  29. Biol. Pharm. Bull. v.22 Simultaneous determination of baicalin, wogonoside, baicalein, wogonin, berberine, coptisine, palmatine, palmatine, jateorrhizine and glycyrrhizin in Kampo medicines by ion-pair high-performance liquid chromatograpgy. Okamura, N.;H. Miki;S. Ishida;H. Ono;A. Yano;T. Tanaka;Y. Ono;A. Yagi
  30. Carcer. Biochem. Biophysics. v.15 Batacarotene prevents lipid peroxidation and red blood cell menbrane protein damage in experimental hapatocarcinogenesis. Sarkar, A,;A. Bishayee;M. Chatterjee
  31. Carcinogenesis. v.9 Activated neutrophils induce prolonged DNA damage in neighboring cells. Shacter, E.;E. J. Beecham;J. M. Covey;K. W. Kohn;M. Potter
  32. Nimsangbonchohak Shin, M. K.
  33. J. Biol. Chem. v.187 Averision of the Shoenheimer-Sperry method for cholesterol determination. Sprry. W. M.;M. Webb
  34. J. Inorganic. Biochem. v.14 The role of superoxide and hydroxyl radical in the degradation of hyaluronic acid induced by metal ions and by ascorbic acid. Wong, S. F.;B. Holliwell;R. Richimond;W. R. Skowroneck
  35. J. Ethopharmacol. v.46 Pharmacological effects of Dai-saiko-to on lipid biosynthesis in cultured human hepatocyte HepG2 cells. Yamamoto, K.;Y. Ogawa;T. Yanagita;F. Mori;N. Fukushima;I. Ozaki;T. Mizuta;Y. Setoguchi;T. Sakai
  36. Planta Med. v.63 Inhibitory effects of Oren-gedoku-to and its components on cholesteryl ester synthesis in cultured human hepatecyte HepG2 cells: evidence from the cultured HepG2 cells and in vitro assay of ACAT. Yotsumoto,H.;T. Yanagita;K. Yamamoto;Y. Ogawa;J. Y. Cha;Y. Mori