생명과학회지 (Journal of Life Science)

  • 제10권1호
  • /
  • Pages.86-93
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  • 2000
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  • 1225-9918(pISSN)
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  • 2287-3406(eISSN)
한국생명과학회 (Korean Society of Life Science)
권호 표지

시클로덱스트린과 아스피린의 포접화합물의 구조와 가수분해에 관한 연구

Structure and Hydrolysis Study of Inclusion Complex of Cyclodextrin and Aspirin

  • 발행 : 2000.02.01
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초록

Specific molecular recognition of cyclodextrin and aspirin was determined. A stable 1:1 inclusion complex was established in solution. The distinct structure of inclusion complex was elucidated by FT-IR, FAB-MS, UV, 1H NMR, and 13C NMR spectroscopy. Based on the 1H NMR data, a time-averaged conformation of $\alpha$-cyclodextrin exhibited significant catalytic activity toward the hydrolysis of aspirin in alkaline solution.

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참고문헌

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