Journal of Life Science (생명과학회지)

Korean Society of Life Science (한국생명과학회)
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The Effects on Quinone ReductaseInduction of Daucus carota L.

당근 추출 성분의 Quinone reductase 유도활성 효과

  • 한은주 (신라대학교 자연과학대학 식품영양학과) ;
  • 노승배 (양산 대학 식품가공과) ;
  • 배송자 (신라대학교 자연과학대학 식품영양학과)
  • Published : 2000.02.01
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Abstract

Chemoprevention is one of the major strategies for cancer control. It is well established that dietary factors play an important role in modulating the development of certain types of human cancer. The experiment was conducted to determine quinone reductase(QR) activity induction of Daucus carota L. on HepG2 cells. Among various partition layers of roots of Daucus carota L., the ethyl acetate partition layer(DCMEA) and the n-hexane partition layer(DCMH) tested to be most effective which resulted 2.1 and 1.6 respectively compared to the control value of 1.0. In the case of seeds of Daucus carota L. n-butanol partition layer (DCMB) on HepG2 cells at a dose of 200 $\mu\textrm{g}$/$m\ell$ showed the highest induction activity of QR which was 3.0. These results suggest that potentially useful cancer chemoprevention chemicals could be isolated from DCMEA and DCMH of the roots and DCMB of the seeds of Daucus carota L.

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