Journal of Microbiology and Biotechnology

  • 제10권3호
  • /
  • Pages.386-393
  • /
  • 2000
  • /
  • 1017-7825(pISSN)
  • /
  • 1738-8872(eISSN)
한국미생물·생명공학회 (The Korean Society for Microbiology and Biotechnology)
권호 표지

New Family of Monoglucosylglyceride Diacyl Glycerol Lipids Containing Very Long Chain bifunctional Acyl Chains in Sarcina ventriculi

  • 발행 : 2000.06.01
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Recent research on the fatty acyl chains in the membrane lipids in Sarcina ventriculi has shown that unusually long chain bifunctional fatty acyl components are the major components of the total lipid. However, these studies did not yield any information on the complete structures of the lipid species containing these fatty acids. In this study, the structures of a new family of glucolipids containing bifunctional acyl chains are described. These structures were determined using NMR(Nuclear Magnetic Resonance) Spectroscopy, GC (Gas Chromatography)/MS (Mass Spectrometry), FTIR (Fourier Transform Infrared) spectroscopy, and FAB (Fast Atom Bombardment) mass spectrometric studies. One of the major bifunctional acyl components of the $\alpha$-glucolipids was an $\omega$-formylmethyl ester indicating the presence of plasmalogen. The general structure of the lipid components was one in which the two head groups were separated by a membrane-spanning acyl species. One head group component is a glycerol moiety of each head group, and the other is a glyceryl clucoside. Two regular chain fatty acids, one on the glycerol moiety of each head group, are also present and meet in the middle of the membrane, roughly equidistant from each head group.

키워드

참고문헌

  1. Biochemistry v.26 Role of substrate in determining the phospholipid specificity of protein kinase C activation Bazzi, M. D.;G. L. Nelsestuen
  2. Cell. v.45 Protein kinase C activation by diacylglycerol second messengers Bell, R. M.
  3. Bergey's Manual of Systematic Bacterology v.2 Genus Sarcina Goodsir 1842, 434 AL Canale-Parola, E.;P. A. Sneath(ed.);N. S. Mair(ed.);M. E. Sharpe(ed.);J. G. Holt(eds.)
  4. J. Bacteriol. v.169 Physiological adaptations of anaerobic bacteria to low pH: Metabolic control of proton motive force in Sarcina ventriculi Goodwin, S.;J. G. Zeikus
  5. J. Microbiol. Biotechnol v.8 Characterization of glycolipid biosurfactants from an isolated strain of Pseudomonas aeruginosa YPJ80 Cho, J. H.;Y. L. Jeong;O. H. Park;B. D. Yoon
  6. Bull. Korean Chem. Soc. v.20 On the unusual homeoviscous adaptation of the membrane fatty acyl components against the thermal stress in Rhizobum meliloti Choi, Y. H.;S. Kang;C. H. Yang;H. W. Kim;S. Jung
  7. J. Biochem. Mol. Biol. v.33 Molecular dynamics simulations of the fatty acid bilayer containing very long chain transmembrane dicarboxylic acids Choi, Y. H.;C. H. Yang;H. W. Kim;S. Jung
  8. Analytical Chemistry Holme, J. D.;H. Peck
  9. J. Lipid Res. v.35 Structures and stereochemistry of the very long α,ω-bifunctional alkyl species in the membrane ofSarcina ventriculi indicate that they are formed by tail-to-tail coupling of normal fatty acids Jung, S.;R. I. Hollingsworth
  10. J. Theor. Biol. v.172 A mathematical model explaining the molecular weights and distribution of very long chain dicarboxylic acids formed during the adaptive reponse of Sarcina ventriculi Jung, S.;R. I. Hollingsworth
  11. J. Biol. Chem. v.268 Sarcina ventriculi synthesizes very long chain dicarboxylic acids in response to different forms of environmental stree Jung, S.;S. E. Lowe;R. I. Hollingsworth;J. G. Zeikus
  12. J. Lipid Res. v.35 A new family of very long chain α,ω-dicarboxylic acids is a major structural fatty acyl component of the membrane lipids of Thermoanaerobacter ethanolicus 39E. Jung, S.;J. G. Zeikus;R. I. Hollingsworth
  13. J. Am. Chem. Soc. v.120 A dynamically regulated transformation of a bacterial bilayer membrane to a cross-linked 2-dimensional sheet during adaptation to unfavorable environmental pressures Lee, J.;S. Jung;S. Lowe;J. G. Zekius;R. I. Hollingsworth
  14. Membrane Fluidity Silvius, J. R.;N. Mark;R. N. McElhaney;M. Kates(ed.);A. Kuksis(eds.)
  15. J. Microbiol. Biotechnol v.4 Isolation, identification, and culture conditions of the strain producing eicosapentaenoic acid Shin, W.;C. Kim;E. Hong