Journal of Acupuncture Research

Korean Acupuncture & Moxibustion Medicine Society (대한침구의학회)
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The Effect of Bee Venom Acupuncture into Chok-samni (ST 36) Formalin-induced Pain Behavior

족삼리(足三里) 봉독약침자극(蜂毒藥鍼刺戟)이 Formalin-induced Pain Behavior 에 미치는 영향(影響)

  • Yim, Yun-Kyoung (Dept. of Acupuncture & Moxibustion Oriental Medical College, Kyung Hee University) ;
  • Seo, Jung-Chul (Dept. of Acupuncture & Moxibustion Oriental Medical College, Kyung Hee University) ;
  • Kim, Yong-Suk (Dept. of Acupuncture & Moxibustion Oriental Medical College, Kyung Hee University) ;
  • Kim, Chang-Hwan (Dept. of Acupuncture & Moxibustion Oriental Medical College, Kyung Hee University) ;
  • Lee, Yun-Ho (Dept. of Acupuncture & Moxibustion Oriental Medical College, Kyung Hee University) ;
  • Choi, Do-Young (Dept. of Acupuncture & Moxibustion Oriental Medical College, Kyung Hee University)
  • 임윤경 (경희대학교 한의과대학 침구학교실) ;
  • 서정철 (경희대학교 한의과대학 침구학교실) ;
  • 김용석 (경희대학교 한의과대학 침구학교실) ;
  • 김창환 (경희대학교 한의과대학 침구학교실) ;
  • 이윤호 (경희대학교 한의과대학 침구학교실) ;
  • 최도영 (경희대학교 한의과대학 침구학교실)
  • Published : 2000.06.20
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Abstract

This study was designed to evaluate the analgesic effect of bee venom (BV) Acupuncture into different treatment points, Chok-samni (ST36) and blank loci of the gluteal muscle and back. We investigated the changes in formalin-induced pain behavior according to the pretreatment with different concentrations of BV, thirty minutes before the formalin injection. The results were summarized as follows: 1. The formalin-induced pain behavior was suppressed by pretreatment with BV into Chok-samni (ST36) in a dose dependent manner. During the early phase, 0.08mg/kg of BV showed a statistically significant suppression in the formalin-induced pain behavior. Moreover, 0.008mg/kg, 0.016mg/kg, and 0.08mg/kg of BV, except 0.0016mh/kg of BV, had significant suppresive effects on the formalin-induced pain behavior during the late phase. Therefore, these data indicated that the suppressive effect of BV acupuncture on the formalin-induced pain behavior was stronger in the late phase rather than the early phase 2. In order to investigate the analgesic effect of BV acupuncture into different treatment points, the experimental animals were divided into three groups: Chok-samni (ST36) group, gluteal group and back group. In the Chok-samni (ST36) group, the formalin-induced pain behavior during all the phases was significantly reduced as compared with that of the back group. However, as compared with that of the gluteal group, the formalin-induced pain behavior in the Chok-samni (ST36) group was decreased only in the late phase, not in the early phase. The formalin-induced pain behavior in the gluteal group was significantly reduced as compared with that of the back group in the late phase, not in the early phase. We suggested that the analgesic effect of BV acupuncture into Chok-samni (ST36) was most effective among Chok-samni (ST36), gluteal, and the back groups in formalin-induced pain behavior.

Keywords

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