Radiation Oncology Journal
- Volume 18 Issue 1
- /
- Pages.27-31
- /
- 2000
- /
- 2234-1900(pISSN)
- /
- 2234-3156(eISSN)
The Results of Hvperfractionated Radiation Therapy Combined with Taxol for Paraaortic Node Recurrence in Cervix Cancer
대동맥주위 림프절에 재발된 자궁경부암에서 Taxol을 병행한 과분할 방사선치료의 결과
- Kim, Jun-Sang (Department of Therapeutic Radiology Chungnam National University) ;
- Jang, Ji-Young (Department of Therapeutic Radiology Chungnam National University) ;
- Kim, Jae-Sung (Department of Therapeutic Radiology Chungnam National University) ;
- Kim, Sam-Yong (Department of Internal Medicine, College of medicine, Chungnam National University) ;
- Cho, Moon-June (Department of Cancer Research Institute, Chungnam National University)
- 김준상 (충남대학교 의과대학 치료방사선과학교실) ;
- 장지영 (충남대학교 의과대학 치료방사선과학교실) ;
- 김재성 (충남대학교 의과대학 치료방사선과학교실) ;
- 김삼용 (충남대학교 의과대학 내과학교실) ;
- 조문준 (충남대학교 의과대학 암공동연구소)
- Published : 2000.03.01
Abstract
Purpose : The aim of this study was to investigate treatment results, toxicity and efficacy of hypefractionated radiation therapy combined with paclitaxel for paraaortic node recurrence in cervix cancer. Materials and Methods: Between September 1997 to March 1999, 12 patients with paraaortic node recurrence in cervix cancer who previously received radical or postoperative radiotherapy were treated with hypefractionated radiation therapy combined with paclitaxel. Of these, 2 patients who irradiated less than 30 Gy were excluded, 10 patients were eligible for this study. Median age was 51 years. Initial FIGO stage was 1 stage IBI, 2 stage IIA, 7 stage IIB. For initial treatment, 7 patients received radical radiotherapy and 3 received postoperative radiotherapy. The paraaortic field encompassed the gross recurrent disease with superior margin at T12, and inferior margin was between L5 and S1 with gap for previously pelvic radiation field. The radiation field was initially anterior and posterior opposed field followed by both lateral field. The daily dose was 1.2 Gy, twice daily fractions, and total radiotherapy dose was between 50.4 and 60 Gy(median, 58.8 Gy). Concurrent chemotherapy was done with paclitaxel as a radiosensitizer. Dose range was from 20 mg/m
목적 : 대동맥주위림프절에 재발된 자궁경부암 환자의 치료방법으로 방사선민감제로 paclitaxel (Taxol)을 병행한 과분할 방사선치료에 대한 치료결과 밑 부작용을 분석하여 치료의 유용성에 대해 알아보고자 하였다 대상 및 방법 : 1997년 9월부터 1999년 3월까지 충남대학교병원 치료방사선과에서 자궁경부암으로 골반부에 근치적 또는 수술 후 방사선치료를 받은 후 대동맥주위림프절에 재발되어 Taxol을 병행한 과분할 방사선치료를 받았던 12명 환자중 30 Gy 이하의 방사선치료를 받은 2명을 제외한 10명을 대상으로 분석을 시행하였다. 대상환자의 연령은 31
Keywords