대한한방내과학회지 (The Journal of Internal Korean Medicine)

대한한방내과학회 (The Society of Internal Korean Medicine)
권호 표지

보양환오탕(補陽還五湯)이 혈전생성관여인자(血栓生成關與因子)에 미치는 영향(影響)

The Effects of Boyanghwanotang on the Thrombosis Related Factors

  • Park, Jong-Hyung (Department of Internal Medicine, College of Oriental Medicine, Kyun-Won University) ;
  • Han, Yang-Hi (Department of Internal Medicine, College of Oriental Medicine, Kyung-Won University) ;
  • Jun, Chan-Yong (Department of Internal Medicine, College of Oriental Medicine, Kyung-Won University) ;
  • Kim, Dong-U (Department of Internal Medicine, College of Oriental Medicine, Kyung-Won University) ;
  • Park, Se-Gi (Department of Internal Medicine, College of Oriental Medicine, Kyung-Won University) ;
  • Lee, Chung-Jung-Hye (Department of Internal Medicine, College of Oriental Medicine, Kyung-Won University) ;
  • Go, Seung-Hi (Department of Internal Medicine, College of Oriental Medicine, Kyung-Won University) ;
  • Go, Jae-Chul (Department of Internal Medicine, College of Oriental Medicine, Kyung-Won University) ;
  • Choi, You-Kyung (Department of Internal Medicine, College of Oriental Medicine, Kyung-Won University) ;
  • Park, Sun-Young (Department of Internal Medicine, College of Oriental Medicine, Kyung-Won University)
  • 발행 : 2000.12.30
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초록

Purpose : To investigate the inhibitory effect of BHE on platelet aggregation and erythrocyte deformability, we performed following experiments. Methods : Concentrated Boyanghwanotang (BHE) was fed to rats for 10days. High dose group was treated with $500{\beta}{\partial}/kg$ and low dose group with $500{\beta}{\partial}/kg$. Results : BHE enhanced the blood filtration rate, reduced the platelet aggregability, inhibited granule release from collagen-stimulated platelet, the prostaglandin syn-thesis in platelet and enhanced erythrocyte deformability. Conclusion : BHE should inhibit thrombos formation due to platlete hyperaggregabili-ty and reduction of erythrocyte deformabi-lity.

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참고문헌

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