뇌졸중환자(腦卒中患者)에 있어서 치료경과(治療經過)에 따른 뇌혈류(腦血流) 변화(變化) - Brain SPECT 결과(結果)를 중심(中心)으로 -

The change of CBF(cerebral blood flow) of CVA patients by oriental medical treatment - Focused on Brain SPECT results -

  • 강화정 (동신대학교 부속한방병원) ;
  • 홍석 (동신대학교 부속한방병원) ;
  • 김종석 (동신대학교 부속한방병원) ;
  • 송호천 (전남대학교병원 핵의학과) ;
  • 범희승 (전남대학교병원 핵의학과) ;
  • 전상윤 (동신대학교 부속한방병원)
  • Kang, Hwa-Jeong (Dong-Shin University Oriental Hospital) ;
  • Hong, Seok (Dong-Shin University Oriental Hospital) ;
  • Kim, Jong-Seok (Dong-Shin University Oriental Hospital) ;
  • Song, Ho-Chon (Department of Nuclear Medicine, Chonnam National University Medical Hospital) ;
  • Bum, Hee-Seung (Department of Nuclear Medicine, Chonnam National University Medical Hospital) ;
  • Jeon, Sang-Yun (Dong-Shin University Oriental Hospital)
  • 발행 : 2000.08.30

초록

Object : SPECT which can visualize the distribution of CBF was operated to find the basic evidence by objective and scientific inspection on the fact that how the oriental medical treatment for stroke patients can effect CBF. Method : This study made 18 cases an object of research. These patients came to the Dongshin Univ. Oriental Medical Hospical within 5 days from the first attack, were diagnosed as stroke from Brain CT and MAl and were in the hospital for over 4 weeks at least. They were taken acupunture treatment, negative technique and herbal medication. And this study operated SPECT at the instance of admission and at the 4th week after admission 2 times and compared the change of CBF. Results : I operated SPECT on 18 CVA patients and got a result on the change of blood supplies in brain as follows; In the 2nd SPECT compared with 1st, out of the 1st and 2nd SPECT, there are 10 cases(55.6%) of increase and 8 cases (44.4%) of decrease. According to L/Cb11 evauation standard, the 1 st and the 2nd changes of blood supplies in SPECT shows decrese from $0.830{\pm}0.071$ to $0.801{\pm}0.067$. On the other hand, according to L/C standard shows a minute increase from $0.894{\pm}0.079$ to $0.895{\pm}0.091$. But there is nothing meaningful. I treated patients' group with risk factors and the other patients' group without risk factors and observed the changes of blood supplies respectively. And therefore Patients' group without risk factors shows an meaningful increase of blood supplies from $0.835{\pm}0.076$ to $0.796{\pm}0.069$ L/Cbll and also an increase from $0.921{\pm}0.029$ to $0.939{\pm}0.029$ by L/C. But this result by L/C is not significant. Conclusion : As mentioned above, I treated CVA patients through oriental medical therapies using SPECT and researched the changes of blood supplies in their brains. But I could' t get any meaningful result. However, I think only after solving some problems in this treatment and quantifing the changes of blood supplies, this results can be the standard of scientific examination about oriental medical treatments.

키워드

참고문헌

  1. 大韓韓醫學會誌 v.14 no.2 中風患者의 半身麻痺 回復度에 대한 臨床的 觀察 高成奎;李京燮
  2. 토絲子가 血壓 및 局所腦血流量에 미치는 影響 金경洙
  3. 大韓韓醫學會誌 v.15 no.1 水溝穴 刺針에 의한 3-次神經興奪 및 血壓上昇이 實驗的 腦梗塞의 局所腦血流量 增加에 미치는 影響 尹相協;柳在煥;洪南斗
  4. 경희의학 v.7 최근 뇌졸중에 대한 역학적 고찰 나영설;윤상협;민병일
  5. 大韓韓方內科學會誌 v.18 no.2 生脈散이 血壓 및 局所腦血流量에 미치는 影響 申大澈;金瑩均;韓宗鉉;文九;金在燮
  6. 死亡原因 統計年譜 第16卷 統計廳
  7. 대한신경과학회지 v.10 no.3 급성 뇌경색 환자의 기능회복에 관한 예비적 연구 김진국;하정상;변영주
  8. 대한의학협회지 v.38 no.6 한국인 5대 사망원인질환의 현황과 추이 金馹舜
  9. 中央醫學 v.46 腦卒中(中風)의 東西醫學的 治療에 關한 硏究 具本泓
  10. 大韓韓醫學會誌 v.18 no.2 腦卒中患者 290 例에 대한 臨床 考察(III) 姜官昊;全燦鎔;朴鍾滎
  11. 白蠶이 血壓 및 局所腦血流量에 미치는 影響 黃勁澤
  12. 補陽環五湯이 血壓 및 局所腦血流量에 미치는 影響 金楠容
  13. 大韓鍼灸學會誌 v.15 no.1 肝 ${cdot}$${cdot}$ 腎兪에 艾灸施術과 Laser光線針이 血壓과 腦血流量에 미치는 影響 趙南根;金庚植
  14. 太平聖惠方 王慶隱
  15. Scand J. Rehab. Med. v.14 Evaluation of the functional capacity of stroke patients through an Activity Index Hamrin, E.;Wohlin, A.
  16. 대한의학협회지 v.36 우리나라 사망원인의 변천과 현황 김정순
  17. 대한의학협회지 v.36 뇌졸중의 사인과 유형별 발생빈도의 추이 이병철
  18. J. Neurol neruosurg Psychiatry v.40 Mood disorder as a specific complication Folstein, M.F.;Naiberger, R.;Mchugh, R.R.
  19. J. Neurol. Neurosurg. Psychiatry v.47 Predicting the outcome of acute stroke : A prgnostic score Allen, C.M.E.
  20. Stroke v.15 The profile of recovery from the stroke and factors influencing outcome Kotila, M.;Walltino, O.;Niemi, M.L.;Lacksonen, R.;Lempinen, M.
  21. Stroke v.7 Recovery of the corical evoked response following temporary middle cerebral artery occlusion on baboons : Relation to local blood glow and PaO2 Branston, N.M.;Symon, L.;Crockard, H.A.
  22. 가톨릭대학 의학부 논문집 v.44 no.4 고양이에서 총뇌혈류 차단후 재관류시기에 따른 국소뇌혈류. 체성감각 유발전위반응 및 뇌부종 정철구;강준기
  23. Stroke v.8 Diaschisis with cerebral infarction Slator, R.;Reivich, M.;Goldberg, H.;Banka, E.;Greenberg, J.
  24. TINS v.11 Motor neuron recovery after lesion Goldberger, M.E.
  25. Stroke v.21 no.1 Pathophysiology of Ischemic Stroke as Determined by PET. Heiss, W.D.
  26. J. Nucl. Med. v.24 Cerebral blood flow tomography : Xenon-133 compared with isopropyl-amphetamine-iodine-123 : concise communication Lassen, N.A.;Henriksen, L.;Holm, S.
  27. Eur. J. Nucl. Med. v.12 Initial experience with SPECT of the brain using 99mTc-hexamethyl propyleneamine oxime(99mTc-HMPAO) Spreafic, G.;Cammelli, F.;Gadola, G.
  28. J. Nuct. Med. v.27 Technetium-99m-d, 1-HM-PAO : A new radiopharmaceutical for imaging regional brain perfusion using SPECT-a comparison with iodine-123 HIPDM Leonard, J.P.;Nowotnik, D.P.;Neirinckx, R.D.
  29. J. Nucl. Med. v.28 Initial experience with technetium-99m HM-PAO brain SPECT Podreka, I.;Suess, E.;Goldenberg, G.;Steiner, M.;Brucke, T.;Muller, C.;Lang, W.;Neirinckx, R.D.;Deecke, L.
  30. J. Nucl. Med. v.29 Technetium-99m HMPAO-SPECT study of regional cerebral perfusion in early Alzheimer's disease Perani, D.;Piero, V.D.;Vallar, G.;Cappa, S.;Messa, C.;Bottini, G.;Berti, A.;Passafiume, D.;Scarlato, G.;Gerundini, P.;Lenzi, G.L.;Fazio, F.
  31. J. Nucl. Med. v.30 Comparative study of regional cerebral blood flow images by SPECT using xenon-133, iodine-123 IMP and technetium-99m HM-PAO Nakano, S.;Kinoshita, K.;Jinnouchi, S.;Hoshi, H.;Watanabe, K.
  32. 대한핵의학회지 v.23 no.2 일과성 뇌허혈 발작 환자에 있어서 99mTc-HMPAO 국소뇌혈류 SPECT의 유용성 안명임;박영하;이성용;정수교;김종우;박용휘
  33. 대한핵의학회지 v.30 no.4 아급성 뇌경색 환자에서 99mTc-ECD 뇌 SPECT : 중례보고. 안병철;이동수;윤병우;소영;정준기;이명철;고창순
  34. 대한핵의학회지 v.22 no.1 뇌혈관질환에서 99mTc-HMPAO SPECT를 이용한 국소뇌혈류의 정량적 분석 이명철;이명혜;고창순;노재규;명호진;이선호(등)
  35. 劉河間三六書 劉完素
  36. 濟生方 嚴用和
  37. 丹溪心法附餘(上) 朱震亨
  38. 景岳全書(卷十) 張介賓
  39. 醫林改錯(卷下) 王淸任
  40. 대한신경과학회지 v.11 no.3 열공성 뇌경색증 : 병변체적 위치, 위험인자에 관한 연구 김동권;이상봉;김재문
  41. 대한신경과학회지 v.16 no.5 뇌졸중 선행인자 : 위험인자의 변동, 선행된 감염, 추위에의 노출, 정신적 스트레스의 역할 정선주;김종성;이창화
  42. Stroke v.19 Diagnostic classification of stroke, especially lacunes Weisberg, L.A.