Journal of the korean academy of Pediatric Dentistry (대한소아치과학회지)
- Volume 27 Issue 3
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- Pages.400-409
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- 2000
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- 1226-8496(pISSN)
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- 2288-3819(eISSN)
ELECTROPHYSIOLOGICAL AND MORPHOLOGICAL CHARACTERISTICS OF FACIAL NUCLEUS IN RAT
흰쥐 안면신경핵 세포의 전기생리학적 및 형태학적 특성
- Choi, Byung-Ju (Department of Dental Pharmacology, College of Dentistry, Kyungpook National University) ;
- Cho, Jin-Hwa (Department of Dental Pharmacology, College of Dentistry, Kyungpook National University) ;
- Bae, Yong-Chul (Department of Oral Anatomy, College of Dentistry, Kyungpook National University) ;
- Kim, Young-Jin (Department of Pediatric Dentistry, College of Dentistry, Kyungpook National University)
- 최병주 (경북대학교 치과대학 치과약리학교실) ;
- 조진화 (경북대학교 치과대학 치과약리학교실) ;
- 배용철 (경북대학교 치과대학 구강해부학교실) ;
- 김영진 (경북대학교 치과대학 소아치과학교실)
- Published : 2000.08.31
Abstract
This study used in vivo intracellular and extracellular field potential recording to evaluate the intrinsic membrane properties and connection pattern within facial nucleus. 1. There were four subdivisions of medial, intermediate, lateral, and dorsolateral in facial nucleus. 2. Principal cells in the facial nucleus was recorded from and filled with neurobiotin in anesthetized rats. The extent of their dendrites and the characteristics of cell body were examined. 3. Principal cells had a large amplitude action potential and afterhyperpolarization was followed a single action potential. 4. The response from facial motonucleus to electrical stimulation of the facial nerve was mainly a monophasic wave, with a latency of 1 msec, which was assumed to reflect antidromic activation of facial motoneurons. In some of rats the response in addition showed late components at a latency of about 7-8 msec, but its amplitude was small. 5 Most of cells exhibited accommodation of spike discharge upon depolarization of membrane by 0.8 nA for 400 ms. Our results support the hypothesis that there normally are weak connections between different parts of the facial motonucleus to explain pathophysiology of hemifacial spasm and facial naive paralysis.
흰쥐의 안면신경핵을 구성하는 신경세포들의 시냅스 연결 양태 및 세포막 특성을 규명하기 위해 in vivo 필드전위 및 세포 내 전위 측정법을 이용하여 전기생리적 반응을 관찰하였다. 말초 안면신경 분지를 역행성으로 전기자극시 자극세기에 비례하여 전위의 크기가 증가되었고 필드 전위의 양태는 두 가지 반응으로 나타났는데 전기자극 직후 1ms 부근에서 정점을 나타내는 양태와 이와 더불어
Keywords