Journal of the Korean Association of Oral and Maxillofacial Surgeons
- Volume 26 Issue 6
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- Pages.557-564
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- 2000
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- 2234-7550(pISSN)
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- 2234-5930(eISSN)
A COMPARATIVE STUDY ON THE STRENGTH AND THE BONE FORMATION AT THE RATS CALVARIAL DEFECTS OF DFDB GRAFT AND THOSE OF THE COMPOSITE GRAFT WITH DFDB AND RESORBABLE HYDROXYAPATITE
백서 두개골 결손부에 동결 건조 동종 탈회골을 단일매식한 경우와 동결 건조 동종 탈회골과 흡수성 수산화인회석을 복합매식한 경우의 강도 및 골형성에 관한 비교 연구
- Seo, Young-Ho (Department of Oral & Maxillofacial Surgery, College of Dentistry, Dankook University) ;
- Yim, Chang-Joon (Department of Oral & Maxillofacial Surgery, College of Dentistry, Dankook University) ;
- Lee, Jae-Il (Department of Oral Pathology, College of Dentistry, Seoul National University)
- Published : 2000.12.31
Abstract
The bone graft materials can be grossly divided into autogenous bone, allogenic bone, xenogenic bone, and alloplastic material. Much care was given to other bone graft materials away from autogenous bone due to its additional operation for harvesting, delayed resorption and limitation of quantity. Demineralized freeze-dried bone(DFDB) and hydroxyapatite are the representatives of bone graft materials. As resorbable hydroxyapatite is developed in these days, the disadvantage of nonresorbability can be overcome. So we planned to study on the strength and the bone formation at the rats calvarial defects of DFDB graft and those of the composite graft with DFDB and resorbable hydroxyapatite. We used the 16 male rats weighting range from 250 to 300 gram bred under the same environment during same period. After we made the 6mm diameter calvarial defect, we filled the DFDB in 8 rats and DFDB and resorbable hydroxyapatite in another 8 rats. We sacrificed them at the postoperative 1 month and 2 months with the periostium observed. As soon as the specimens were delivered, we measured the compressive forces to break the normal calvarial area and the newly formed bone in calvarial defect area using Instron(Model Autograph
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