Journal of the Korean Association of Oral and Maxillofacial Surgeons
- 제26권1호
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- Pages.53-58
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- 2000
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- 2234-7550(pISSN)
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- 2234-5930(eISSN)
구강암에 대한 약용식물 추출물의 항암효과에 관한 연구
STUDIES ON ANTI-ORAL CANCER ACTIVITIES OF MEDICINAL PLANT EXTRACTS
- Lee, Young-Hoon (Dept. of OMFS, College of Dentistry, Kyung-Hee University) ;
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Kim, Yeo-Gab
(Dept. of OMFS, College of Dentistry, Kyung-Hee University) ;
- Kim, Jung-Hee (Dept. of Oral Biochemistry, College of Dentistry, Kyung-Hee University)
- 발행 : 2000.02.28
초록
Treatment of oral cancers with chemotherapeutic agents are evaluated as an effective method for remission to reduce cancer proliferation nowadays. But, minimization of side-effects such as bone marrow suppression, gastrointestinal toxicity and renal damage is another problem to be solved. Thus, a possible approach to develop a clinically applicable chemotherapeutic agents is to screen anticancer activity among traditional medicinal plants which have been used for thousands of years with very low side-effects in orient. In this study we focused on screening anti-oral cancer activities among 14 traditional medicinal plant extracts that revealed anticancer activities on other solid tumors. The results were as follow : 1. Methanol extract of Lepidium apetalum showed the highest anti-oral cancer activity against A253 cells. At concentration of