Journal of Pharmaceutical Investigation
- Volume 30 Issue 4
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- Pages.283-288
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- 2000
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- 2093-5552(pISSN)
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- 2093-6214(eISSN)
HPLC Analysis of Retinol in the Biological Fluids and Cutaneous Absorption after its Transdermal Administration
레티놀의 생체시료 중 HPLC 분석 및 경피흡수
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Chung, Youn-Bok
(College of Pharmacy, Chungbuk National University) ;
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Han, Kun
(College of Pharmacy, Chungbuk National University)
- Published : 2000.12.20
Abstract
The purpose of the present study was to investigate the topical bioavailability of retinol (vitamin A) after its transdermal administration. For this purpose, we developed the convenient HPLC method to measure the retinol concentration in the biological fluids such as plasma and skin tissues. The low detection limit was