Journal of Pharmaceutical Investigation
- 제30권4호
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- Pages.283-288
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- 2000
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- 2093-5552(pISSN)
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- 2093-6214(eISSN)
레티놀의 생체시료 중 HPLC 분석 및 경피흡수
HPLC Analysis of Retinol in the Biological Fluids and Cutaneous Absorption after its Transdermal Administration
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Chung, Youn-Bok
(College of Pharmacy, Chungbuk National University) ;
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Han, Kun
(College of Pharmacy, Chungbuk National University)
- 발행 : 2000.12.20
초록
The purpose of the present study was to investigate the topical bioavailability of retinol (vitamin A) after its transdermal administration. For this purpose, we developed the convenient HPLC method to measure the retinol concentration in the biological fluids such as plasma and skin tissues. The low detection limit was