한국식품과학회지 (Korean Journal of Food Science and Technology)
- 제32권3호
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- Pages.726-735
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- 2000
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- 0367-6293(pISSN)
목질진흙버섯 자실체와 배양 균사체 유래 ${\beta}-Glucan$ 성 다당류의 생리활성
Biological Activities of Polysaccharide Extracted from the Fruit Body and Cultured Mycelia of Phellinus linteus IY001
- 이준우 (경북전문대학 식품가공과) ;
- 백성진 (일양약품 중앙연구소 생물공학팀) ;
- 방광웅 (경북전문대학 식품가공과) ;
- 강신욱 (경북전문대학 식품가공과) ;
- 강상모 (건국대 미생물공학과) ;
- 김병용 (경희대 식품가공학과) ;
- 하익수 (일양약품 중앙연구소 생물공학팀)
- Lee, June-Woo (Department of Food Science & Technology, Kyungbuk College) ;
- Baek, Sung-Jin (Biotechnology Lab., Central Research Institute, Il Yang Pharm. Co Ltd.) ;
- Bang, Kwang-Woong (Department of Food Science & Technology, Kyungbuk College) ;
- Kang, Shin-Wook (Department of Food Science & Technology, Kyungbuk College) ;
- Kang, Sang-Mo (Department of Microbiological Engineering, Konkuk University) ;
- Kim, Byung-Yong (Department of Food Science & Technology, Kyunghee University) ;
- Ha, Ick-Su (Biotechnology Lab., Central Research Institute, Il Yang Pharm. Co Ltd.)
- 발행 : 2000.06.30
초록
목질진흙버섯 자실체와 배양 균사체의 열수추출 및 열수 추출물의 에탄올, UF처리 분획들에 대한 약리 효과를 조사하여 다음과 같은 결과를 얻었다. Sarcoma 180 암세포 증식 저지율은 자실체 열수 총 분획(Fr. I)보다 비교적 고분자인 다당류 분획(Fr. II, Fr. III, Fr. IV)에서
This study was conducted to investigate the biological activities of polysaccharide extracted from the fruit body and cultured mycelia of Phellinus linteus IY001. All fractions were extracted by hot water, in the next, Fr. I, Fr. II, Fr. III and Fr. IV were polysaccharide obtained by ethanol precipitation or ultrafiltration. The highest antitumor activity against sarcoma 180 in ICR mice was observed in Fr. III and Fr. IV at the level 85%, but the antitumor activity had no connection with their anticomplementary activity in vitro, it might probably be due to extraction of hot water. All fractions promoted the production of nitric oxide and