Korean Journal of Pharmacognosy (생약학회지)
- Volume 31 Issue 3
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- Pages.264-267
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- 2000
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
Anti-HIV-1 Protease Activity and in Vivo Anti-lipid Peroxidative Effect on Rosa davurica
생열귀나무의 항 HIV-1 protease 작용과 생체내 과산화지질생성 저해효과
- Kim, Suk-Nam (Jungsun-RoseHip, Yongtan-ri) ;
- Chang, Kwang-Jin (Department of Industrial Crops, Korea National Agricultural College, RDA) ;
- Choi, Jong-Won (Department of Pharmacy, Kyungsung University) ;
- Park, Jong-Cheol (Department of Oriental Medicine Resources, Sunchon National University)
- Published : 2000.09.30
Abstract
Anti-human immunodeficiency virus (HIV) type I protease (PR) and anti-lipid peroxidation effects on Rosa davurica were investigated. Of the various parts tested from R. davurica, the water extracts of stem and leaves inhibited the HIV-1 PR activity by more than 45% at a concentration of
Keywords
- Rosa davurica;
- Rosaceae;
- HIV-1 protease;
- protease inhibitor;
- bromobenzene-induced rat;
- lipid peroxidation