생약학회지 (Korean Journal of Pharmacognosy)

  • 제31권3호
  • /
  • Pages.325-334
  • /
  • 2000
  • /
  • 0253-3073(pISSN)
  • /
  • 2288-9299(eISSN)
한국생약학회 (The Korean Society of Pharmacognosy)
권호 표지

Cyclophosphamide로 Rat에 유도된 악성빈혈에 대한 숙지황의 증(蒸)수에 따른 치료효능에 관한 연구

Hemopoietic Effects of Rhizoma Rehmanniae Preparata on Cyclophosphamide-Induced Pernicious Anemia in Rats

  • 하창수 (한국화학연구소 안전성연구센터) ;
  • 성현제 (한국한의학연구원 연구부) ;
  • 지옥표 (성균관대학교 약학대학) ;
  • 마진열 (한국한의학연구원 연구부)
  • Ha, Chang-Su (Toxicology Research Center, Research Institute of Chemical Technology) ;
  • Sung, Hyun-Jea (Korea Institute of Oriental Medicine) ;
  • Zee, Ok-Pyo (College of Pharmacy, Sung kyun Kwan University) ;
  • Ma, Jin-Yeul (Korea Institute of Oriental Medicine)
  • 발행 : 2000.09.30
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Rhizoma Rehmanniae Preparata is a Chinese herbal tonic. The hemopoietic effects of Rhizoma Rehmanniae Preparata(4-time steamed Jihwang, 4-time steamed double dose Jihwang, 8-time steamed Jihwang, 8-time steamed double dose Jihwang) were examined using in vitro rat(SD) model. Cyclophosphamide(150 mg/kg) was injected into experimental groups and control group to induce bone marrow suppression. Oral administration of Rhizoma Rehmanniae Preparata suppressed hormone levels of $T_4\;and\;T_3$. Reticulocyte count was increased by the bone marrow suppression.

키워드