생약학회지 (Korean Journal of Pharmacognosy)
- 제31권1호
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- Pages.57-62
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- 2000
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
양강으로부터 COX-2 억제활성물질의 분리
Isolation of COX-2 Inhibitors from Alpinia officinarum
- 김주선 (서울대학교 천연물과학연구소) ;
- 손건호 (안동대학교 식품영양학과) ;
- 김현표 (강원대학교 약학대학) ;
- 장현욱 (영남대학교 약학대학) ;
- 강삼식 (서울대학교 천연물과학연구소)
- Kim, Ju-Sun (Natural Products Research Institute, Seoul National University) ;
- Son, Kun-Ho (Department of Food and Nutrition, Andong National University) ;
- Kim, Hyun-Pyo (College of Pharmacy, Kangwon National University) ;
- Chang, Hyeun-Wook (College of Pharmacy, Yeungnam University) ;
- Kang, Sam-Sik (Natural Products Research Institute, Seoul National University)
- 발행 : 2000.03.30
초록
By bioassay-guided fractionation followed by chromatographic separation of the MeOH extract of Alpinia Rhizome, five COX-2 inhibitors were isolated and characterized as pinocembrin, galangin 3-methyl ether, galangin, kaempferid, and 5-hydroxy-7-(4'-hydroxy-3'-methoxyphenyl)-1-phenyl-3-heptanone.
키워드