The Korean Journal of Physiology and Pharmacology
- 제4권4호
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- Pages.319-324
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- 2000
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- 1226-4512(pISSN)
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- 2093-3827(eISSN)
Effect of Heat Shock Protein 72 on the Generation of Reperfusion Arrhythmias
- Chang, Moon-Jun (Department of Physiology, Korea University College of Medicine) ;
- Na, Heung-Sik (Department of Physiology, Korea University College of Medicine) ;
- Nam, Hyun-Jung (Department of Physiology, Korea University College of Medicine) ;
- Pyun, Kyung-Sik (Department of Physiology, Korea University College of Medicine) ;
- Hong, Seung-Kil (Department of Physiology, Korea University College of Medicine)
- 발행 : 2000.08.21
초록
The causal relationship between heat shock protein (HSP) and second window of cardioprotective effect is still undetermined. In the present study, we assessed whether HSP-producing substances, amphetamine and ketamine, afforded protection against reperfusion-induced ventricular fibrillation (VF) and these protective effect remained after the inhibition of HSP72 production by quercetin, a mitochondrial ATPase inhibitor. Adult mongreal male cats
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