약학회지 (YAKHAK HOEJI)
- 제44권6호
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- Pages.499-504
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- 2000
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
흰쥐 척수에서 지속성 진통물질 6-파라돌에 의한 아데노신의 유리 증가
Induction of Adenosine Release by 6-Paradol, a Long Lasting Analgesic, in Rat Spinal Cord
- Yoo, Eun-Sook (College of Medicine, Cheju National University) ;
- Kim, Ok-Hee (National Institute of Toxicological Research) ;
- Lee, Sang-Sup (College of Pharmacy, Seoul National University)
- 발행 : 2000.12.30
초록
We previously demonstrated that 6-paradol, a compound structurally related to capsaicin, showed to produce prolonged analgesia in experimental animals. The effects of 6-paradol on the release of adenosine were investigated in the rat spinal cord synaptosomes by high performance liquid chromatography. In the presence of