생물정신의학 (Korean Journal of Biological Psychiatry)
- 제6권1호
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- Pages.135-140
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- 1999
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- 1225-8709(pISSN)
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- 2005-7571(eISSN)
Clozapine 투여 후 경련성 발작을 보인 환자 1례
A Case of Convulsive Seizure Development Induced by Clozapine
- 서만길 (성균관대학교 의과대학 삼성서울병원 신경정신과학교실) ;
-
김도관
(성균관대학교 의과대학 삼성서울병원 신경정신과학교실)
;
- 김이영 (성균관대학교 의과대학 삼성서울병원 신경정신과학교실)
- Seo, Man Kil (Department of Neuropsychiatry, College of Medicine, SungKyunKwan University, Samsung Medical Center) ;
-
Kim, Doh Kwan
(Department of Neuropsychiatry, College of Medicine, SungKyunKwan University, Samsung Medical Center)
;
- Kim, Eyong (Department of Neuropsychiatry, College of Medicine, SungKyunKwan University, Samsung Medical Center)
- 발행 : 1999.06.25
초록
The authors described a case of male schizophrenia who developed myoclonic jerk repeatedly and one episode of convulsive seizure during the treatment of clozapine. According to literatures and reported cases, myoclonic jerks induced in a small amount of clozapine may precede and predict the development of a convulsive seizure. Therefore clinicians have to pay attention to the development of a myoclonic jerk during the administration of clozapine. They may decrease the dosage of clozapine step by step at first in the convulsive state, and observe EEG changes of patients frequently.