Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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A Case of Multiple Thromboembolisms in Hyperhomocysteinemia

과호모시스턴혈증에서 발생된 다발성 혈전증 1예

  • Park, Jae-Sun (Department of Internal Medicine, College of Medicine, Inje University) ;
  • Bae, Won-Ki (Department of Internal Medicine, College of Medicine, Inje University) ;
  • Lee, Sang-Jun (Department of Internal Medicine, College of Medicine, Inje University) ;
  • Chung, Rae-In (Department of Internal Medicine, Armed Forces Capital Hospital) ;
  • Jin, Seong-Lim (Department of Internal Medicine, College of Medicine, Inje University) ;
  • Lee, Hyuk-Pyo (Department of Internal Medicine, College of Medicine, Inje University) ;
  • Kim, Joo-In (Department of Internal Medicine, College of Medicine, Inje University) ;
  • Choi, Soo-Jeon (Department of Internal Medicine, College of Medicine, Inje University) ;
  • Yum, Ho-Kee (Department of Internal Medicine, College of Medicine, Inje University)
  • 박재선 (인제대학교 의과대학 내과학교실) ;
  • 배원기 (인제대학교 의과대학 내과학교실) ;
  • 이상준 (인제대학교 의과대학 내과학교실) ;
  • 정내인 (국군수도병원 내과) ;
  • 진성림 (인제대학교 의과대학 내과학교실) ;
  • 이혁표 (인제대학교 의과대학 내과학교실) ;
  • 김주인 (인제대학교 의과대학 내과학교실) ;
  • 최수전 (인제대학교 의과대학 내과학교실) ;
  • 염호기 (인제대학교 의과대학 내과학교실)
  • Published : 1999.08.30
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Abstract

Hyperhomocysteinemia is an independent risk factor for cardiovascular, cerebrovascular and peripheral vascular diseases complicated with atherosclerosis and thromboembolism. Increased plasma homocystein level develops from genetic defect of enzyme for homocystein metabolism or vitamine deficiency, has direct toxic effect for vascular endothelium and makes damages to antithrombotic action of vascular endothelial cell. Most of hyperhomocysteinemia is asymptomatic, but rarely develops cardiopulmonary or cerebrovascular accidents. In case of thromboembolism with unknown cause, the hyperhomocysteinemia should be considered as one of the many etiologies. The authors, first in korea, report a case of multiple thromboembolisms of deep vein of lower extremity, pulmonary vessels, superior sagittal and transverse sinus of brain in a patient with the hyperhomocysteinemia with a review of literature.

저자등은 우하지 동통 및 객혈을 주소로 내원하여 우하지 심부정맥혈전증, 폐색전증 및 뇌정맥혈전증으로 환자에서 과호모시틴혈증이 다발성 혈전증의 원인이었던 1예를 경험 하였기에 문헌고찰과 함께 보고하는 바이다.

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