Maxillofacial Plastic and Reconstructive Surgery
- Volume 21 Issue 2
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- Pages.89-109
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- 1999
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- 2288-8101(pISSN)
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- 2288-8586(eISSN)
STUDY OF RAT EPIGASTRIC VESSELS ACCORDING TO THE FREEZING TIME : HISTOLOGIC, HISTOMORPHOMETRIC, IMMUNOHISTOCHEMICAL & SCANNING ELECTRON MICROSCOPIC STUDY
백서 상복부 혈관의 동결시간에 따른 변화에 대한 연구
- Kim, Woo-Chan (Dept. of Oral and Maxillofacial Surgery, Collage of Dentistry, Dankook University) ;
- Lee, Chong-Heon (Dept. of Oral Pathology, Collage of Dentistry, Dankook University) ;
- Kim, Kyung-Wook (Dept. of Oral and Maxillofacial Surgery, Collage of Dentistry, Dankook University) ;
- Kim, Chang-Jin (Dept. of Pathology, Collage of Medicine, Soonchunhyang University)
- 김우찬 (단국대학교 치과대학 구강악안면외과학교실) ;
- 이종헌 (단국대학교 치과대학 구강병리학교실) ;
- 김경욱 (단국대학교 치과대학 구강악안면외과학교실) ;
- 김창진 (순천향대학교 의과대학 병리학교실)
- Received : 1999.01.05
- Accepted : 1999.02.05
- Published : 1999.06.30
Abstract
Vascular spasm which has been reported to occur in 25% of clinical cases continues to be a problem in microvascular surgery; When prolonged and not corrected, it can lead to low flow, thrombosis, and replant or free flap failure. Ischemia, intimal damage, acidosis and hypovolemia have been implicated as contributors to the vascular spasm. Although much work has been done on the etiology and prevention of vasospasm, a spasmolytic agent capable of firmly protecting against or reversing vasospasm has not been found. Therefore vascular freezing was introduced as a new safe method that immediately and permanently relieves the vasospasm and can be applied to microsurgical transfers. Cryosurgery can be defined as the deliberate destruction of diseased tissue or relief the vascular spasm in microvascular surgery by freezing in a controlled manner. 96 Sprague Dawley rats each weighing within 250g were used and divided into 2 group, experimental 1 and 2 group. In the experimental 1 group, right epigastric vessels (artery and vein) were freezed with a cryoprobe using
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