Journal of Haehwa Medicine (혜화의학회지)
- Volume 8 Issue 1
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- Pages.793-825
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- 1999
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- 2586-3002(pISSN)
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- 2586-3347(eISSN)
Study on pathology of Alzheimer's disease, trends and future strategy for research
치매의 병리(病理), 연구동향(硏究動向)과 향후(向後) 연구전략(硏究戰略)에 대(對)한 고찰(考察)
- Oh, Young-Sun (Hae-Hwa Clinic of Taejon University Hospital,Taejon University) ;
- Kim, Sung-Hoon (Department of Oriental Pathology,Taejon University)
- Published : 1999.09.01
Abstract
For the development of drugs for alzheimer,s disease, the study was done to review the oriental pathology, clinical data, recent trends for research and strategy for future study. The results were as follows: 1. The medical term Chi-dsi implying alzheimer,s disease was referred for the first time in a medical book, Hwatasheneubijeon written by Hwa-Ta and its differentiation and treatment were studied more in Ming or Ching dynasties. Chi-dai can be differentated as weak(虛) syndrome and Shi(實) syndrome. This can be caused by deficiencies of renal Yin, renal Yang, cardiac Yin and hepatic blood, while that by deficiencies of pathological fluid(痰飮) and clotted blood(瘀血). 2. Dementia can be roughly classified as alzheimer's disease and multi-infarct disease. Its causes were known to be cholinergic transmitter, C-peptide, amyloid-