Korean Journal of Veterinary Research (대한수의학회지)
- Volume 39 Issue 2
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- Pages.287-293
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- 1999
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- 2466-1384(pISSN)
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- 2466-1392(eISSN)
Isoeugenol prevents N-methyl-D-aspartate(NMDA)-induced neurotoxicity and convulsion
- Wie, Myung-bok (Department of Veterinary Medicine, College of Agriculture and Institute of Life Science, Cheju National University)
- Received : 1999.01.24
- Published : 1999.04.01
Abstract
Isoeugenol, one of the phenylpropanoid derivatives has been known to inhibit the lipid peroxidation via scavenging effect on hydroxyl or superoxide radical production. We examined whether isoeugenol has a inhibitory effect against N-methyl-D-aspartate(NMDA)-, oxygen/glucose deprivation- and xanthine/xanthine oxidase(X/XO)-induced neurotoxicity or NMDA-induced
Keywords
- isoeugenol;
- N-methyl-D-aspartate;
- oxygen/glucose deprivation, xanthine/xanthine oxidase;
- $^{45}Ca^{+2}$ uptake