대한수의학회지 (Korean Journal of Veterinary Research)
- 제39권2호
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- Pages.257-266
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- 1999
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- 2466-1384(pISSN)
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- 2466-1392(eISSN)
Pharmacokinetics and tissue residues of ivermectin in swine
- Park, Kwon-moo (College of Veterinary Medicine, Seoul National University) ;
- Park, Jln-bong (College of Medicine, Chonbuk National University) ;
- Li, Long-hua (College of Veterinary Medicine, Seoul National University) ;
- Han, Seong-kyu (College of Veterinary Medicine, Seoul National University) ;
- Lee, Hye-sook (National Veterinary Research and Quarantine Service) ;
- Park, Jong-myung (National Veterinary Research and Quarantine Service) ;
- Chang, Byoung-sun (Biotech Research Institute II, LG Chemical Ltd.) ;
- Lee, Mun-han (College of Veterinary Medicine, Seoul National University) ;
- Ryu, Pan-dong (College of Veterinary Medicine, Seoul National University)
- 투고 : 1999.09.01
- 발행 : 1999.04.01
초록
Ivermectin is a widely used broad spectrum antiparasitic agent in veterinary medicine. In this work, we examined the pharmacokinetic parameters and the tissue residue profile of a new injectable formulation of ivermectin developed for pigs. The plasma ivermectin levels reached the peak at about 9 and 2 hours after the administrations in young and adult pigs, respectively. But the elimination half-life (3-3.5 days) and the