Korean Journal of Fisheries and Aquatic Sciences (한국수산과학회지)
- Volume 32 Issue 4
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- Pages.507-511
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- 1999
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- 0374-8111(pISSN)
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- 2287-8815(eISSN)
Biological Activities of Extracts from Crucian Carp
붕어 고음추출물의 생리활성
- KIM Chan-Hee (Dept of Biotechnology and Bioengineering, Pukyong National University) ;
- SEO Jung-Kil (Dept of Biotechnology and Bioengineering, Pukyong National University) ;
- GO Hye-Jin (Dept of Biotechnology and Bioengineering, Pukyong National University) ;
- PARK Nam Gyu (Dept of Biotechnology and Bioengineering, Pukyong National University) ;
- CHUNG Joon-Ki (Dept of Aquatic Life Medicine, Pukyong National University) ;
- HWANG Eun-Young (Dept. of Food and Life Science, Pukyong National University) ;
- Ryu Hong-Soo (Dept. of Food and Life Science, Pukyong National University)
- 김찬희 (부경대학교 생물공학과) ;
- 서정길 (부경대학교 생물공학과) ;
- 고혜진 (부경대학교 생물공학과) ;
- 박남규 (부경대학교 생물공학과) ;
- 정준기 (부경대학교 수산생명의학과) ;
- 황은영 (부경대학교 식품생명과학과) ;
- 류홍수 (부경대학교 식품생명과학과)
- Published : 1999.07.01
Abstract
The pharmacological effects of hydrocooked extracts of crucian carp have been investigated. All of the hydrocooked extracts showed the contractile effect on the isolated rat duodenum and decreased to a certain extent the normal blood pressure in anesthetized rat. The hydrocooked extracts also exhibited a dose-dependent relaxation on the isolated rat aorta precontracted with 50 mM KCl. All of these except for RM 60 fraction haying cytotoxic effect against MCF-7 human breast cancer cell showed neither antibacterial activity nor antitumor activity. In addition, we found that although body weight gain in the hydrocooked extracts treated group were all reduced significantly compared to control group, there were no significant changes in the hematological parameters, except that the levels of high-density lipoprotein was significantly increased. These results suggest that the hydrocooked extracts of crucian carp may contain a variety of bioactive materials.
Keywords
- crucian carp meat;
- contractile effect;
- blood pressure;
- antibacterial activity;
- antitumor activity;
- hematological parameters