Journal of Periodontal and Implant Science
- 제29권3호
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- Pages.469-484
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- 1999
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- 2093-2278(pISSN)
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- 2093-2286(eISSN)
흡수성 차폐막과 동종탈회동결건조골 이식에 의한 치조골 재생의 병용효과
Alveolar Bone Formation in Dogs using Vicryl Absorbable Mesh(Polyglactin 910) and Decalcified Freeze-Dried Bone Grafting
- 오은정 (전남대학교 치과대학 치주과학교실, 전남대학교 치의학 연구소) ;
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정현주
(전남대학교 치과대학 치주과학교실, 전남대학교 치의학 연구소) ;
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김영준
(전남대학교 치과대학 치주과학교실, 전남대학교 치의학 연구소)
- Oh, Eun-Chung (Department of Periodontology, College of Dentistry, Chonnam National University Institute of Dentistry, College of Dentistry, Chonnam National University) ;
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Chung, Hyun-Ju
(Department of Periodontology, College of Dentistry, Chonnam National University Institute of Dentistry, College of Dentistry, Chonnam National University) ;
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Kim, Young-Jun
(Department of Periodontology, College of Dentistry, Chonnam National University Institute of Dentistry, College of Dentistry, Chonnam National University)
- 발행 : 1999.09.30
초록
The purpose of this study was to evaluate new bone formation following guided bone regeneration by resorbable and nonresorbable membrane. Six adult mongrel dogs were used. The first, second, third, fourth premolars in the mandible of each dog were extracted. Two months after tooth extraction, a buccal dehiscence defect was surgically created on each edentulous area. The experimental sites were divided into three groups according to the treatment modalities ; Group I-a: surgical treatment only ; Group I -b: allogenic decalcified freezed dried bone grafting ; Group II-a : e- PTFE membrane placement only ; Group II-b : allogenic decalcified freezed dried bone grafting and e-PTFE membrane placement ; Group III-a : Vicryl(R) mesh placement only ; Group III-b : allogenic decalcified freezed dried bone grafting and Vicryl(R) mesh placement . The animals were sacrificed at 8 weeks after operation and the specimens were prepared for histologic and histometric examination. The results were as follows : Clinically, all defect sites were healed without exposure of barrier membrane after the eight weeks. In Group I-a, dense connective tissues were impinged in the bony defect area. Well vascularized and fibrous bone marrow indicated that bone formation was still taking place was found. In Group I-b, in areas closer to the periphery, lamellation of the newly formed bone would found. In Group II-a, beneath the e-PTFE membrane a dense layer of connective tissue covering the most external portions of the regenerated tissue was seen. The new bone surfaces were lined with osteoid and osteoblast. In Group II-b, a dense layer of connective tissue covering the most external portions of the regenerated tissue was observed beneath the e-PTFE membrane. A notable amount of alveolar ridge regeneration was seen with new rigdes with well-contoured form. In Group III-a, the new bone surface were lined with osteoid and osteoblast, indicating active bone formation. A clear demarcation could not be noted between the host bone and new bone. In Group III-b, a notable amount of alveolar ridge regeneration was seen with new ridges assuming wellcontoured form. In areas closer to the periphery, lamellation of the newly formed bone would found. As histometric examination, the amount of bone formation was gained from
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