Journal of Periodontal and Implant Science
- 제29권1호
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- Pages.141-151
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- 1999
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- 2093-2278(pISSN)
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- 2093-2286(eISSN)
염화 세틸피리디늄 분말의 치태제거와 치은염 완화 효과에 관한 임상시험
Effect of Cetylpyridinium Chloride on Gingival Inflammation and Plaque Accumulation
- 전형식 (서울대학교 치과대학 치주과학교실) ;
- 고영경 (서울대학교 치과대학 치주과학교실) ;
- 구영 (서울대학교 치과대학 치주과학교실) ;
- 류인철 (서울대학교 치과대학 치주과학교실) ;
- 최상목 (서울대학교 치과대학 치주과학교실) ;
- 정종평 (서울대학교 치과대학 치주과학교실)
- Jun, Hyung-Sik (Department of Periodontology, College of Dentistry, Seoul National University) ;
- Ko, Young-Kyung (Department of Periodontology, College of Dentistry, Seoul National University) ;
- Ku, Young (Department of Periodontology, College of Dentistry, Seoul National University) ;
- Rhyu, In-Chul (Department of Periodontology, College of Dentistry, Seoul National University) ;
- Choi, Sang-Mook (Department of Periodontology, College of Dentistry, Seoul National University) ;
- Chung, Chong-Pyoung (Department of Periodontology, College of Dentistry, Seoul National University)
- 발행 : 1999.03.30
초록
To evaluate the effect of cetylpyridinium chloride in a powder form when used concomitantly with a commercial flouride containing tooth paste on inhibition of plaque formation, on gingivitis, and on irritation of oral mucosa, a double--blind, randomized parallel study was set up. Cetylpyridinium chloride was incorporated into a ligh brown colored powder with menthol added for scent. There were no diffemces between the active agent and the placebo which did not contain cetylpyridinium chloride in appearance, color, smell, taste, or dispenser. 98 healthy volunteers were assigned to one of two groups: brushing 3 times a day with flouride toothpaste and cetylpyridinium chloride powder, or brushing 3 times a day with flouride toothpaste and placebo. Before the test period, the subjects received through tooth cleaning and polishing. At basteline, GI, PI, BOP, and GCF of the Ramfjord teeth were measured in the experimental and placebo groups including 58 and 42 subjects repectively, After 4 weeks, GI, PI, BOP, GCF, compliance, irritation of the oral mucosa(redness, pus drainage, edema) and adverse reactions were measured. The PI, GI, and BOP of the experimental group recorded at baseline are 0.19