Analytical Science and Technology (분석과학)

The Korean Society of Analytical Sciences (한국분석과학회)
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A Study on Determination of Iodine in Serum, Fresh Milk, and Feed Additive by Inductively Coupled Plasma-Mass Spectrometry

유도결합 플라스마-질량분석법에 의한 혈청, 생우유 및 사료첨가제중 요오드의 분석에 관한 연구

  • Lee, Won (Research Instituted for Basic Sciences and Department of Chemistry, Kyunghee University) ;
  • Park, Kyung-Su (Research Instituted for Basic Sciences and Department of Chemistry, Kyunghee University) ;
  • Kim, Sun-Tae (Advanced Analysis Center, Korea Institute of Science and Technology) ;
  • Kim, Young-Man (Advanced Analysis Center, Korea Institute of Science and Technology)
  • 이원 (경희대학교 기초과학연구소 문리과학대학 화학과) ;
  • 박경수 (경희대학교 기초과학연구소 문리과학대학 화학과) ;
  • 김선태 (한국과학기술연구원 특성분석센터) ;
  • 김영만 (한국과학기술연구원 특성분석센터)
  • Received : 1999.06.28
  • Published : 1999.12.25
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Abstract

The total iodine is determined in serum, fresh milk and feed additive by ICP-MS. The preparation involves only a 25-fold dilution with a diluent by direct nebulization in the plasma. The diluent composition is $NH_4OH$(0.5% v/v)+$CH_3OH$(5% v/v) and the abundance of iodine is measured at m/z=127. The calibration curve was linear over the ranges $0-100{\mu}g/L$ with $R^2=0.99$ for iodine. The detection limit of this method is $0.084{\mu}g/L$ for iodine. The relative error range of milk powder SRM in optimum condition is 2.30%-4.73%. The concentration ranges of iodine in the serum, fresh milk, feed additive were $12.4-40.2{\mu}g/L$, < 0.01-3.11 mg/L, < $10^{-7}-2.60g/kg$ respectively.

유도결합 플라스마-질랑분석법을 이용하여 혈청, 생우유 및 사료첨가제 중 요오드를 정량하였다. 시료를 매트릭스 변형제인 $NH_4OH$(0.5% v/v)+$CH_3OH$(5% v/v) 혼합용액으로 25배 묽힌 다음, m/z=127에서 이온세기를 측정하였다. 이 방법에 대한 요오드의 검정곡선은 $0-100{\mu}g/L$ 범위에서 상관계수($R^2$)가 0.99인 직선관계를 나타내었으며, 검출한계는 $0.084{\mu}g/L$이었다. 최적 분석 및 기기 조건에서 분유 표준시료를 분석한 결과 상대오차는 2.30-4.73% 범위이었다. 또한 혈청, 생우유, 동물의 사료 첨가제 등과 같은 실제시료를 분석한 결과 요오드의 함유량은 각각 $12.4-40.2{\mu}g/L$, < 0.01-3.11 mg/L,< $10^{-7}-2.60g/kg$ 범위이었다.

Keywords

Acknowledgement

Supported by : 한국학술진흥재단

References

  1. Mikrochim. Acta v.116 Peter Schramel;Sylvia Hasse
  2. Analyst v.105 R. E. D. Moxon;E. J. Dixon
  3. J. Assoc. Off. Anal. Chem. v.69 no.4 Peter W. F. Fischer;Mary R. Labbe;Alexandre Giroux
  4. Analyst v.117 M. Dermelj;Z. Slejkovec;A. R. Byme;P. Stegnar
  5. Analyst v.118 Raghunadha R. Rao;Amares Chatt
  6. Anal. Chem. v.38 no.8 G. A. Rechnitz;M. R. Kresz;S. B. Zamochnick
  7. Anal. Chem. v.47 no.12 Eric A. Crecelius
  8. Analytica Chimica Acta v.274 Marcel Langenauer;Urs Krahenbuhl;Armin Wyttenbach
  9. Anal. Chem. v.63 no.24 Shuxun Yang;Shoujun Fu;Minlu Wang
  10. Journal of Chromatography B v.673 H. S. Lee;J. S. Lee;H. Lee;Y. S. Jung;Patrick P. DeLuca;K. C. Lee
  11. Journal of Chromatography B v.692 Soren Andersson;Ulf Forsman
  12. Analyst v.97 A. W. Archer
  13. J. Assoc. Off. Anal. Chem. v.73 no.5 Takao Mitsuhashi;Yoshio Kaneda
  14. Journal of Analytical Atomic Spectrometry v.9 Taketoshi Nakahara;Toshio Mori
  15. J. Anal. Chem. v.352 R. Wennrich;A. Mroczek;K. Dittrich;G. Werner, Fresenius
  16. Analyst v.115 Pierre Allain;Yves Mauras;Christophe Douge;Laurent Jaunault
  17. Analyst v.118 Hans Vanhoe;Francoise Van Allemeersch;Jacques Versieck;Richard Dams
  18. Journal of Analytical Atomic Spectrometry v.12 Erik H. Larsen;Merete B. Ludwigsen
  19. Anal. Chem. v.42 R. H. Kaiser