Two Cases of Hemolytic Uremic Syndrome Associated with Pneumococcal Infection

폐렴구균 감염에 동반된 비전형적 용혈성 요독 증후군 2례

  • Jo Seung-Heui (Department of Pediatrics, Seoul National University College of Medicine) ;
  • Park Kyung-Mi (Department of Pediatrics, Seoul National University College of Medicine) ;
  • Ha Il-Soo (Department of Pediatrics, Seoul National University College of Medicine) ;
  • Cheong Hae-Il (Department of Pediatrics, Seoul National University College of Medicine) ;
  • Choi Yong (Department of Pediatrics, Seoul National University College of Medicine)
  • 조승희 (서울대학교 의과대학 소아과학교실) ;
  • 박경미 (서울대학교 의과대학 소아과학교실) ;
  • 하일수 (서울대학교 의과대학 소아과학교실) ;
  • 정해일 (서울대학교 의과대학 소아과학교실) ;
  • 최용 (서울대학교 의과대학 소아과학교실)
  • Published : 1999.10.01

Abstract

Hemolytic uremic syndrome is a clinical syndrome with various etiology and pathogenesis. And pneumococcal neuraminidase has been known to play a pathogenetic role in some cases with this syndrome. We experienced two children with hemolytic uremic syndrome complicated by pneumococcal infection. One was 21-month-old girl with pneumococcal pneumonia, and the other was 7-month-old girl with pneumococcal meningitis and sepsis. Both of them showed typical clinical manifestations of hemolytic uremic syndrome with prolonged anuria during the course of pneumococcal infection. The renal functions of both cases did not recovered after resolution of acute hemolytic episode and chronic renal failure developed.

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