한국 산악지역에서 채집한 야생들쥐의 한타바이러스 감염에 대한 혈청역학적 연구

Seroepidemiological Study on Hantavirus Infection of Wild Rodents Captured in the Moutainous Areas of Korea

  • 백락주 (고려대학교 의과대학 미생물학교실, 고려대학교 바이러스병연구소) ;
  • 김광섭 (고려대학교 대학원) ;
  • 송기준 (고려대학교 의과대학 미생물학교실, 고려대학교 바이러스병연구소) ;
  • 고은영 (고려대학교 의과대학 미생물학교실, 고려대학교 바이러스병연구소) ;
  • 정기모 (고려대학교 의과대학 미생물학교실, 고려대학교 바이러스병연구소) ;
  • 박광숙 (고려대학교 의과대학 미생물학교실, 고려대학교 바이러스병연구소) ;
  • 이용주 (고려대학교 의과대학 미생물학교실, 고려대학교 바이러스병연구소) ;
  • 송진원 (고려대학교 의과대학 미생물학교실, 고려대학교 바이러스병연구소)
  • Baek, Luck-Ju (Department of Microbiology, College of Medicine, Institute for Viral Diseases, Korea University) ;
  • Kim, Kwang-Seop (Graduate School, Korea University) ;
  • Song, Ki-Joon (Department of Microbiology, College of Medicine, Institute for Viral Diseases, Korea University) ;
  • Kho, Eun-Young (Department of Microbiology, College of Medicine, Institute for Viral Diseases, Korea University) ;
  • Chung, Ki-Mo (Department of Microbiology, College of Medicine, Institute for Viral Diseases, Korea University) ;
  • Park, Kwang-Sook (Department of Microbiology, College of Medicine, Institute for Viral Diseases, Korea University) ;
  • Lee, Yong-Ju (Department of Microbiology, College of Medicine, Institute for Viral Diseases, Korea University) ;
  • Song, Jin-Won (Department of Microbiology, College of Medicine, Institute for Viral Diseases, Korea University)
  • 발행 : 1999.03.30

초록

Hantaan virus is widely distributed among rodent populations in Korea. Two antigenically distinct hantaviruses were isolated from Apodemus agrarius in 1976 and Rattus norvegicus in 1980 in Korea. This study was designed to investigate the serological evidence of hantavirus infection among indegenous wild rodents, which were captured in 11 mountains located in Kyunggi, Kangwon, Chungnam, Chunbug and Kyungnam province of South Korea. A total 252 wild rodents of 3 species were trapped from Myungsung Mt., Chumbong Mt., Kali Mt., Hansuk Mt., Chachil peak, Kyebang Mt., Odae Mt., Kyerong Mt., Kaya Mt., Togju Mtand Chiri Mtin 1997. Serologic test for hantavirus infection was performed using hantavirus antigens by indirect immunofluorescent antibody techniqueAmong 122 Apodemus agrarius, 88 Apodemus peninsulae and 42 Eothenomys regulus; 18 A. agrarius (14.8%), 12 A. peninsulae (13.6%) and 4 E. regulus (9.5%) were immunofluorescent antibody (IFA) positive against hantaan virus. IFA titers 3 Eothenomys regulus sera were higher against puumalavirus than hantaan virus. These data imply that above three species of rodent might be natural reservoirs of hantaviruses in Korea.

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