The Korean Journal of Pesticide Science (농약과학회지)
- Volume 3 Issue 1
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- Pages.20-28
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- 1999
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- 1226-6183(pISSN)
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- 2287-2051(eISSN)
Synthesis and biological activities of Chloronicotinyl derivatives
Chloronicotinyl 유도체의 합성 및 생물활성 검정
- Park, Su-Jin (Division of Biological Environment, College of Agriculture and Life Sciences, Kangwon National University) ;
- Kim, In-Hae (Division of Biological Environment, College of Agriculture and Life Sciences, Kangwon National University) ;
- Choi, In-Young (Daeduck Science Town, Dongbu Advanced Research Institute) ;
- Kim, Song-Mun (Division of Biological Environment, College of Agriculture and Life Sciences, Kangwon National University) ;
- Han, Dae-Sung (Division of Biological Environment, College of Agriculture and Life Sciences, Kangwon National University) ;
- Hur, Jang-Hyun (Division of Biological Environment, College of Agriculture and Life Sciences, Kangwon National University)
- 박수진 (강원대학교 농업생명과학대학 자원생물환경학부) ;
- 김인해 (강원대학교 농업생명과학대학 자원생물환경학부) ;
- 최인영 (동부기술원) ;
- 김성문 (강원대학교 농업생명과학대학 자원생물환경학부) ;
- 한대성 (강원대학교 농업생명과학대학 자원생물환경학부) ;
- 허장현 (강원대학교 농업생명과학대학 자원생물환경학부)
- Published : 1999.05.25
Abstract
Chloronicotinyl derivatives were synthesized by substitution of amino in 3-pyridylmethylamine with phosphite groups and their insecticidal and fungicidal activities were determined. At 500 ppm, compound 4 with methyl and butyl group in phosphonate and compound 5, 6, 7, and 8 with two butyl, 2,2,2-trifluorotehtyl, 2-ethylhexyl, phenyl, respectively, in phosphonate showed 90% insecticidal activities against brown plant-hopper (Nilaparvate lugens). These compounds showed, however, poor insecticidal activities against diamond-back moth (Plutella xylostella) and two-spotted spider mite (Tetranychus urticae) (<65%), suggesting that insecticidal activity of chloronicotinyl derivatives containing phosphorus moieties are species-dependent. Newly synthesized chloronicotinyl derivatives with halogen and/or heterocycle (compound
Chloronicotinyl 유도체의 기본 골격인 3-pyridylmethylamine의 amine기를 phosphite group으로 치환하여 chloronicotinyl 유도체를 합성하였고, 이들의 살충활성과 살균활성을 확인하였다. 살충활성 검정 결과, 500 ppm 에서 phosphonate에 methyl기와 butyl기가 치환된 compound 4와 2개의 butyl, 2,2,2-trifluorotehtyl, 2-ethylhexyl, phenyl기가 치환된 compound 5, 6, 7, 8이 벼멸구에 대해서 90%의 살충활성을 나타내었다. 그러나 이들 화합물들은 배추좀나방과 두점박이응애에 대해서는 낮은 살충활성을 나타내었으며, phosphonate에 halogen이나 heterocycle이 치환된 compound