농약과학회지 (The Korean Journal of Pesticide Science)
- 제3권3호
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- Pages.27-36
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- 1999
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- 1226-6183(pISSN)
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- 2287-2051(eISSN)
살충제 Carbofuran과 Phenobarbital Sodium 및 3-Methylcholanthrene이 쥐의 효소활성에 미치는 영향
Effect of Insecticide Carbofuran and Phenobarbital Sodium and 3-Methylcholanthrene on Activity of Enzyme in Rat
- Rim, Yo-Sup (Department of Agricultural Chemistry, College of Agriculture, Sunchon National University) ;
- Han, Seong-Soo (Department of Agricultural Chemistry, College of Life Science and Natural Resources, Wonkwang University)
- 발행 : 1999.12.30
초록
쥐에 있어서 carbamate계 살충제 carbofuran의 독성에 미치는 phenobarbital sodium(PB) 또는 3-methylcholanthrene(3-MC)의 영향과 작용기작을 효소적 측면에서 구명할 목적으로 이들을 단독 또는 조합으로 경구투여 하여 in vivo 효소활성을 조사하였다. Acetylcholinesterase(AChE)와 butyrylcholinesterase(BuCheE)의 효소활성은 carbofuran 3.8 mg/kg을 투여하였을 때 48시간까지
Effect of insecticide carbofuran and phenobarbital sodium(PB) or 3-methylcholanthrene(3-MC), they were orally administered by the chemicals, alone or in combination, on activities of several enzymes in rats were investigated. In in vivo test for the effect of this chemicals on activity of enzyme in rat, activities of acetylcholinesterase(AChE) and butyrylcholinesterase(BuCheE) were inhibited by