대한핵의학회지 (The Korean Journal of Nuclear Medicine)

대한핵의학회 (The Korean Society of Nuclear Medicine)
권호 표지

$^{111}In$-Pentetreotide 스캔으로 진단 가능했던 가스트린종을 가진 Zollinger-Ellison 증후군 1예

A Case of Zollinger-Ellison Syndrome with Gastrinoma Localized by $^{111}In$-Pentetreotide Scan

  • 정현조 (대림성모병원 진단방사선과) ;
  • 류진숙 (울산대학교 의과대학 서울중앙병원 핵의학과) ;
  • 김재승 (울산대학교 의과대학 서울중앙병원 핵의학과) ;
  • 문대혁 (울산대학교 의과대학 서울중앙병원 핵의학과) ;
  • 정훈용 (울산대학교 의과대학 서울중앙병원 내과) ;
  • 하현권 (울산대학교 의과대학 서울중앙병원 진단방사선과) ;
  • 이희경 (울산대학교 의과대학 서울중앙병원 핵의학과)
  • Jeong, Hyeon-Jo (Department of Diagnostic Radiolosy, Dae Rim St. Mary's Hospital) ;
  • Ryu, Jin-Sook (Departments of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Jae-Seung (Departments of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Moon, Dae-Hyuk (Departments of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Jung, Hwoon-Yong (Departments of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Ha, Hyun-Kwon (Departments of Diagnostic Radiology, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Lee, Hee-Kyung (Departments of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine)
  • 발행 : 1999.12.30
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초록

In patient with Zollinger-Ellison syndrome, it is difficult to localize gastrinoma because the tumor is frequently small and multiple. However, accurate localization of the tumor is important for the treatment Among various imaging modalities, somatostatin receptor scintigraphy (SRS) has been recognized to be the most sensitive tool for the detection of neuroendocrine tumors such as gastrinomas based on the presence of high-affinity binding sites for somatostatin. Recently, we experienced a case of Zollinger-Ellison syndrome caused by gastrinomas which was localized by SRS. This is the first case report of gastrinoma detected by SRS in Korea. SRS can facilitate tumor detection in patient with Zollinger-Ellison syndrome and should be considered as the first-line diagnostic method in the early course of the disease.

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