대한핵의학회지 (The Korean Journal of Nuclear Medicine)
- 제33권4호
- /
- Pages.388-397
- /
- 1999
- /
- 1225-6714(pISSN)
만성 간질환에서 Propranolol의 문맥압 감소 효과: 경직장 문맥 신티그라피를 이용한 평가
Effect of Propranolol on Portal Vein Pressure in Patients with Chronic Liver Disease: Evaluation by Perrectal Portal Scintigraphy
- 노영호 (국립경찰병원 내과) ;
- 한신 (국립경찰병원 내과) ;
- 김학수 (국립경찰병원 내과) ;
- 윤수진 (국립경찰병원 내과) ;
- 김윤권 (국립경찰병원 내과) ;
- 김소연 (국립경찰병원 내과) ;
- 김영중 (국립경찰병원 내과) ;
- 조민구 (국립경찰병원 내과) ;
- 박병익 (국립경찰병원 내과) ;
- 이권전 (국립경찰병원 내과)
- Rho, Young-Ho (Department of Internal Medicine, National Police Hospital) ;
- Han, Shin (Department of Internal Medicine, National Police Hospital) ;
- Kim, Hak-Su (Department of Internal Medicine, National Police Hospital) ;
- Yoon, Su-Jin (Department of Internal Medicine, National Police Hospital) ;
- Kim, Yun-Kwon (Department of Internal Medicine, National Police Hospital) ;
- Kim, So-Yon (Department of Internal Medicine, National Police Hospital) ;
- Kim, Yeong-Jung (Department of Internal Medicine, National Police Hospital) ;
- Cho, Min-Koo (Department of Internal Medicine, National Police Hospital) ;
- Park, Byong-Yik (Department of Internal Medicine, National Police Hospital) ;
- Lee, Gwon-Jun (Department of Internal Medicine, National Police Hospital)
- 발행 : 1999.08.30
초록
목적: Propranolol은 비선택적
Purpose: Propranolol is known to decrease portal pressure by reducing blood flow of portal vein. Perrectal portal scintigraphy with Tc-99m pertechnetate has been introduced to evaluate the portal circulation and early diagnosis of liver cirrhosis. We evaluated the effects of propranolol on portal circulation by using per-rectal portal scintigraphy. Materials and Methods: We analyzed the portal hemodynamics by per-rectal portal scintigraphy in 51 patients with liver cirrhosis, 10 chronic hepatitis and 10 normal subjects. 38 patients with cirrhosis underwent per-rectal portal scintigraphy before and after propranolol medication. Perrectal portal scintigraphy was performed after per-rectal administration of 370 MBq of Tc-99m pertechnetate. The shunt index was calculated as the ratio, expressed as a percentage of heart radioactivity to the sum of heart and liver radioactivity during the first 30 seconds. Results: The shunt index in 40 patients with cirrhosis (