Journal of Photoscience

한국광과학회 (Korean Society of Photoscience)
권호 표지

LIGHT DEPENDENT CHANNELS AND EXCHANGER IN THE INTERNAL LIMITING MEMBRANE OF VERTEBRATE EYE

  • Hyuk Jung (Department of Biochemistry, Kyungpook National University) ;
  • Kim, You-Young (Department of Biochemistry, Kyungpook National University)
  • 발행 : 1999.06.01
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초록

Calcium has a variety of functions in neuron and muscle cells and blood clotting, especially in the visual system where dark adapted rods cotransport with Na$\^$+/ into the cell. An influx of Ca$\^$++/ flows out of the cell through the Na$\^$+/-Ca$\^$++/ exchanger. By using a modified Using chamber in order to bring in vivo environment close, we have known that Ca$\^$++/ blocks the activity of guanylate cyclase, in consequence, having an effect on the amplitude of electroretinogram (ERG). We have measured the Ca$\^$++/, K$\^$+/, and Na$\^$+/ concentration in dark and light adapted bullfrog＇s (Rana catesbeiana) vitreous humor. The calcium concentration of the light adapted bullfrog＇s vitreous humor was higher than that of the dark adapted bullfrog＇s vitreous humor This means that ion activity between the photoreceptor and vitreous humor side is light dependent and we have found that a Ca$\^$++/ channel and Ca$\^$++/K$\^$+/ exchanger exist in the vitreous humor side. Taken together permeability of Ca$\^$++/, K$\^$+/ and K$\^$+/ ion internal limiting membrane faced in the vitreous humor side has light-dependent activity during the illumination.

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참고문헌

  1. Medical Physiology(9th ed.) Guyton, A. C.;J. E. Hall
  2. Proc. Natl. Acad. Sci. USA v.85 Lagnado, L.;L. Cervetto;P. A. McNaughton
  3. Science v.268 Ghosb, A.;M. E. Greenberg
  4. Review of Medical Physiology(6th ed.) Ganong, W. F.
  5. Exp. Eye. Res. v.55 Szabo, M. E.;M.T. Droy-Lefaix;M. Doly;P. Braquet
  6. Nature Dowling, J. E.;H. Ripps
  7. Nature v.313 Yau, K.-W.;Nakatani, K.
  8. Proc. Natl. Acad. Sci. USA v.83 Gold, G. H
  9. Nature v.334 Yau, K.-W.;Nakatani, K.
  10. Sodium-Calcium Exchange Allen, T. J.;A. D. Noble;H. Reuter
  11. Nature v.311 Yau, K. W.;K. Nakatani
  12. J. Physiol. v.391 Hodgkin, A. L.;P. A. McNaughton;B. J. Nunn
  13. Nature v.334 Nakatani, K.;K. W. Yau
  14. Biochemistry v.18 Fleischman, D.;M. Denisevich
  15. J. Gen. Physiol. v.76 Robinson, P. R.;S. Kawamura;B. Abramson;M. D. Bownds
  16. Brain Research v.113 Ehinger, B.;B. Lindberg-Bauer
  17. J. Physiol. v.376 Schwartz, E. A.
  18. Proc. Natl. Acad. Sci. USA v.82 Zimmerman, A.;G. Yamanaka;F. Eckstein;Baylor, D. A.;L. Stryer
  19. Nature v.334 Koch, K.-W.;L. Stryer
  20. Proc. Natl. Acad. Sci. USA v.84 Torre, V.;H. R. Matthews;T. D. Lamb
  21. Science v.268 Ghosb, A.;M. E. Greenberg
  22. Cell v.80 Clapham, D. E.
  23. Science v.258 Heginbotham, L.;T. Abramson;R. MacKinnon
  24. J. Photoscience v.3 Jung, H.;Y. S. Kim;Y. Y. Kim
  25. J. Photoscience v.3 Kim, Y. S.;H. Jung;Y. Y. Kim
  26. J. Physiol. v.358 Hodgkin, A. L.;P. A. McNaughton;B. J. Nunn
  27. An Approachable part of the Brain Dowling, J. E. Retina