Immunohistochemistry of Glucagon- immunoreactive Cells in the Developing Pancreas of the Korean Native Goat (Capra hircus)

  • Sae-Kwang Ku (Laboratory of Histology, College of Veterinary Medicine, Kyungpook National University) ;
  • Hyeung-Sik Lee (Department of Biology, Faculty of Basic Sciences, Kyungsan University) ;
  • Jae-Hyun Lee (Laboratory of Histology, College of Veterinary Medicine, Kyungpook National University)
  • 발행 : 1999.06.01

초록

The distribution of glucagon-immunoreactive cells in the pancreas during various developmental stages (fetus, neonate, 1-month-old, 6-month-old and adult) of the Korean native goat was investigated by immunohistochemical methods. The varying distribution and frequency of glucagon-immunoreactive cells in the pancreas of the Korean native goat were observed. The glucagon-immunoreactive cells were detected in both exocrine and endocrine portions (pancreatic islets) at all developmental stages and also in ducts of the 6-month-old and adult. The relative frequencies of glucagon-immunoreactive cells increased in the pancreatic islets and ducts with age, but decreased in the exocrine portions. Generally, they were distributed in the interacinar spaces or marginal zone of the pancreatic islets during all stages of development. However, the cell distributions of the pancreatic islets in the neonate divided into two types: 1) ones which were distributed in the inner zone, and 2) others in the peripheral zone.

키워드

참고문헌

  1. Textbook of Veterinary Histology(3rd Ed.) Dellmann H;Brown EM
  2. J Histochem Cytochem v.24 Pancreatic islet cell hormone distribution of cell types in teh islet and evidence for the presence of somatostatin and gastrin within the D cells Erlandson SL;hegre OD;Parsons JA;McEvoy RC;Elde RT
  3. Arch Histol Jpn v.42 Development of pancreatic endocrine cells in the rat fetus Fujii S
  4. Okajima Folia Anat Jpn v.72 Immunohistochemical analysis of the endocrine cells in the pancreatic islets of cattle Hirastuka T;Abe M;Takehana K;Iwasa K;hiraga T;Kobayahi A
  5. Veterinary Endocrinology and Reproduction The endocrine pancreas Hsu WH;Crump MH;McDonald LE(ed.);Pineda MH(ed.)
  6. Anat Rec v.196 Distribution and morphometric quantitative of pancreatic endocrine cell types in the frog, Rana pipens Kaung HC;Elde RP
  7. Acta Anat v.135 immunohistochemical study of the developing endocrine pancrease of the opossum (Didelphis virginiana) Krause WJ;Cutts JH Ⅲ;Cutts JH;Yamada J
  8. Hitochemistry v.44 Distribution and properties of glucagon immunoreactivity in the digestive tract of various mammals: a immunohistochemical and immunochemial study Larsson LI;Holst J;Hakanson R;Sundler F
  9. Korean J Vet Res v.35 Immunohistochemical study on the insulin-, glucagon-, somatostatin- and pancreatic polypeptide secreting cells in Korean native goat Lee HS;Lee IS;Kang TC;Kim JS;Yi SJ
  10. Korean J Vet Res v.32 Immunohistochemical studies of the pancreatic endocrine cells of the various animals Lee JH;Lee HS
  11. Acta Anat v.131 Immunochistochemical study on the endocrine pancreas of cattle with special reference to coexistence of serotonin and glucagon or bovine pancreatic polypeptide Nakajima S;Kitamura N;Yamada J;Yamashita T;Watanage T
  12. The Visera of the Domestic Mammals(2nd Ed.) Nickel R;Schummer A;Seiferle E
  13. Eur J Cell Biol v.38 Cellular distribution of insulin, glucagon, pancreatic polypeptide hormone and somatostatin in the fetal and adult pancreas of the guinea pig: a comparative immunohistochemical study Reddy SN;Bibby NJ;Elliott RB
  14. Anat Rec v.208 Immunochistochemical localization of four hormones in the pancreas of the garter snake, Thamnophis sirtalis Rhoten WB
  15. Immunocytochemistry(3rd Ed.) Sternberger LA
  16. J Histochem v.34 Distribution of glucagon like peptide Ⅰ in canine and feline pancreas and gastrointestinal tract Vaillant CR;Lund PK
  17. Exp Toxicol Pathol v.50 A comparative immunohistochemical study of pancreatic islets in laboratory animals (rats, dogs, minipigs, nonhuman primates) Wieczoreck G;Pospischil A;Perentes E
  18. Arch Histol Jpn v.46 Gastro-enteropancreatic (GEP) endocrine system of the flatfish, Paralichyts olivaceus: an immunocytochemical study Yoshida K;Iwanaga T;Fujita T