Maternal Serum Zinc Concentration and Pregnancy Outcomes

임신기 모체의 혈청 아연 농도와 임신 결과

  • 안홍석 (성신여자대학교 식품영양학과)
  • Published : 1999.03.01

Abstract

A study was conducted on a group of 107 women, attending the three peripheral community clinics in Seoul and Kyunggi area for their prenatal care, to ascertain the relationship between maternal serum zinc concentration measured in pregnancy and several pregnancy outcomes. The serum zinc concentration was adjusted for estimated gestational age at the time of drawing blood. Mean daily zinc intake of the pregnant women estimated by a 24-hour recall method was 7.68$\pm$3.70$\mu\textrm{g}$/dl, 51% of RDA. and mean serum zinc concentration of the women was 94.03$\pm$36.99ug/dl. Adjusted maternal serum zinc level was significantly related to gestational maternal weight gain(p<0.05) and infant birth weight(p<0.05). Pregnant women with tgreater than 9kg weight gain during the gestation period had higher adjusted serum zinc levels than the subjects with less than 8kg weight gain. Adjusted serum zinc levels of mothers who delivered 3.0-3.5kg and greater than 4.0kg birth-weight infants were higher than those of mothers of low-birth-weight infants. Any association between maternal serum zinc level and gestational length, complications and morning sickness was not observed. There results suggest that the maternal serum zinc level may predict perhaps the author could be none specific.

Keywords

References

  1. Present in nutrition(7th ed.) Zinc Cousins RJ;Ziegler EE;Filer LJ
  2. Zinc-clinical and biochemical significance Zinc metabolism in animals Cunnane SC
  3. Nutrient regulation during pregnancy, lactation and infant growth Molechular basis for abnornal parturition in zinc deficiency in rats Bunce GE;Lytton B;Gunesekera B;Vessal M;Kim C;Allen L(ed.);King J(ed.);Lonnerdla B(ed.)
  4. Developmental nutrition Hurley LS
  5. Zinc-clinical and biochemical significance Assessment of Zinc nutriture Cunnane SC
  6. Principles of nutritional assessment Assessment of zinc status Gibson RS
  7. Sungshin Journal v.27 A study on the serum zinc levels of Korean pregnant women Ahn HS
  8. Clinical applications of recent advances in zinc metabolism Zinc status and pregnancy outcome in human Jameson S;Prazad AS(ed.);Dreosti IE(ed.);Hetzel BS(ed.);Alan R(ed.)
  9. Clinical applications of recent advances in zinc metabolism Maternal zinc status and pregnancy outcome McMichael AJ;Dreosti IE;Gibson GT;Prazad AS(ed.);Dreosit IE(ed.);Hetzel BS(ed.);Alan R(ed.)
  10. Am J Obstet Gynecol v.128 Fetal malnutrition. Anappraisal of correlated factors Crosby WM;Metcoff J;Costloe JP
  11. Acta Vitaminol Enzymol v.7 no.3-4 Maternal plasma proteins. magnesium. zinc and copper concentrations at term associated with birth size in Kuwait Mameesh MS;Hathout H;Safar MAAI;Mahfouz A
  12. Early Hum Dev v.7 A prospective study of serial maternal serum zinc levels and pregnancy outcome McMichael AJ;Dreosti IE;Gibson GT;Hartshore JM;Buckley RA;Colley DP
  13. Am J Clin Nutr v.34 Maternal nutrition and fatal outcome Metcoff J;Castiloe JP;Corsby W(et al.)
  14. Am J Clin Nutr v.40 Zinc supplementation during pregnancy : Effects on selected blood constituents and on progress and outcome of pregnancy in low income woman of Mexican descent Hunt FH;Murphy NH;Cleaver AE
  15. Hygiea v.86 no.4 Copper, zinc and taste threhold measurements in pregnancy Jameson S;Widstrm A;Ursing I;Barny S;Ohlsson A
  16. J Korean Home Economics v.25 no.4 A study on dietary changes during pregnancy Park MH;Ahn HS
  17. Korean Social Index Office of National Statistics
  18. Recommended dietary allowance for Koreans The Korean Nutrition Society
  19. Korean J Comm Nutr v.1 no.2 Ecological studies of maternal-infant nutrition and feeding in urban low income areas I. Anthropometric measurements, dietary intakes and serum lipids content / fatty acids composition of the pregnants Ahn HS;Park YS;Park SH
  20. Korean J Nutrition v.31 no.8 The effect of weekly iron and zinc nutritional status in pregnant women Yu KH;Yoon JS
  21. Korean J Nutrition v.29 no.10 The relationship between dietary intakes, serum levels, urinary excretions of Zn, Cu, Fe and serum lipids in Korean rural adults on self-selected diet Lee JY;Choi MK;Sung CJ
  22. Korean J Nutrition v.26 no.9 Dietary zinc analysis and changes of zinc nutriture with zinc supplementation in Korean adults Park JS;Chyun JH
  23. Korean J Comm Nutr v.2 no.1 Zinc status of adult female in the Taegu region as assessed by dietary intake and urinary excretion Oh HM;Yoon JS
  24. Am J Clin Nutr v.32 Dietary zinc intake of low-income pregnant women of Maxican descent Hunt IF;Murphy NJ;Gomez J;Smith JC
  25. Br J Nutr v.42 Zinc deficiency in the west of Scotland? A dietary intake study Lyon TDB
  26. Br J Nutr v.38 Daily intake of mananese, copper, zinc, and cadnium by New Zealand women Guthrie BE;Robinson MF
  27. Korean J Nutr v.26 no.3 The study on concentrations of plasma zinc and copper of nonpregnant and pregnant in Korea Ha EJ;Na HB
  28. Obstet Gynecol v.44 no.5 Changes in plasma and hair concentration of zinc, copper, chronium and manganese during pregnancy Hambidge KM;Mrcp(ed.);Droegemueller W;Facog MD
  29. Am J Clin Nutr v.34 Zinc concentration in hair and serum of pregnant women in Belfest Shelia CV;Love AHG;Thompson W
  30. Am J Clin Nutr v.33 Effect of nutrition on serum zinc concentration during pregnancy in Turkish women Cavdar OS;Babacan E;Arcasoy A
  31. Am J Clin Nutr v.51 A positive association between maternal serum zinc concentration and birth weight Neggers YH;Cutter GR;Action RT
  32. Am J Clin Nutr v.37 First trimester serum zinc concentrations in human pregnancy Breskin MW;Worthington-Roberts BS;Knopp RH(et al.)
  33. Am J Clin Nutr v.37 Zinc nutritional status during pregnancy ; A longitudinal study Hambidge KM;Krebs NF;Jacobs MA;Favier A;Guyette L;Ikle DN
  34. Lancet v.2 Plasma-zinc and copper in pregnancy and after oral contraceptives Halsted JA;Hackley BM;Smith JC
  35. Clin Sci Mol Med v.51 Diminished albumin binding of zinc in serum or pregnant women Giroux E;Schechter PJ;Schoun J
  36. Obstet Gynecol v.62 Reduced serum zinc concentration during pregnancy Swanson CA;King JC
  37. Pro Nutr Sci v.43 Factors affecting plasma Zinc and Copper in pregnancy Tuttle S;Aggett PJ;Doris MC;MacGillivary I
  38. Acta Med Scand[Supple] v.593 Zinc and copper in pregnancy. Correlation to fetal and maternal complications Jameson S
  39. Glynecol Obstet Invest v.17 The role of calcium, copper, iron and zinc in preterm delivery and premature rupture of fetal membranes Kiilholma P;Gronroos M;Erkkola R;Parkarrinen P;Nanto V
  40. Am J Clin Nutr v.34 Plasma zinc in hypertention / toximia and other reproductive variables in adolescent pregnancy Cherry FF;Bennett EA;Bazzano GS;Johnson DK;Fosmire GJ;Batson HK
  41. Am J Clin Nutr v.41 Zinc and copper nutrition in human pregnancy : A longitudinal study in normal primigravidae and in primigravidai at risk of delivering a growth retarded baby Tuttle S;Aggett PJ;Campbell D;MacGellivary I