한국미생물·생명공학회지 (Microbiology and Biotechnology Letters)

  • 제27권3호
  • /
  • Pages.223-229
  • /
  • 1999
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  • 1598-642X(pISSN)
  • /
  • 2234-7305(eISSN)
한국미생물·생명공학회 (The Korean Society for Microbiology and Biotechnology)
권호 표지

Singular Approximation과 Minimum Principle을 이용한 발효공정의 최적화

Optimization of Fermentation Processes with Singular Approximation and Minimum Principle

  • 발행 : 1999.06.01
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초록

The two optimal control algorithms, singular approximation and minimum principle, were compared in this paper. The switching time with singular approximation was determined with mathematical derivation and the optimal control profile of specific growth rate was also calculated with minimum principle. The optimal control profiles were calculated by making simple model correlating the specific cell growth rate and specific product formation rate. The optimal control profiles calculated by singular approximation approach were similar to stepwise form of those calculatd by minimum principles. With the minimum principle, the product concentration was 8% more than that of singular approximation. This performance difference was due to a linearization of a nonlinear function with singular approximation. This optimal approaches were applicable to any system with different optimal cell growth and product formation.

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참고문헌

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