생명과학회지 (Journal of Life Science)

  • 제9권5호
  • /
  • Pages.537-547
  • /
  • 1999
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  • 1225-9918(pISSN)
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  • 2287-3406(eISSN)
한국생명과학회 (Korean Society of Life Science)
권호 표지

사회.심리적 스트레스에 미치는 다시마 (Laminaria japonica)와 후코이단 음료의 영향

Effects of Sea Tangle (Laminaria japonica) and Fucoidan Beverages on Sociopsychological Stress

  • 최진호 (부경대학교 식품생명공학부 생화학연구실) ;
  • 김대익 (부경대학교 식품생명공학부 생화학연구실) ;
  • 박수현 (부경대학교 식품생명공학부 생화학연구실) ;
  • 김동우 (부경대학교 식품생명공학부 생화학연구실) ;
  • 이종수 (부경대학교 식품생명공학부 생화학연구실) ;
  • 유종현 (한림제약(주) 중앙연구소) ;
  • 정유섭 (한림제약(주) 중앙연구소)
  • 발행 : 1999.10.01
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초록

This study was designed to investigate the effects of sea tangle (Laminaria japonica) extract (Dasi-Ex group: dry base 4.0%) and fucoidan-added (Fuco-I, II, III group: fucoidan of 1.0%, 2.0%, 3.0% added to Dasi-Ex) beverages on the anti-stress action. ICR male mice (20$\pm$2g) were fed basic experimental diets and given free through water bottle filled with these beverages instead of water for 18 days including sociopsychological stress. Body weight gains were consistently lower in Dasi-Ex and Fuco-I,II,III groups compared with control group, expecting in a inhibitory effect of obesity. Dasi-Ex group resulted in a significant decrease of 25% in serum corticosterone (CS) secretion, while Fuco-I,IIand IIIgroups resulted in a marked decreases of 45~55% in serum CS secretion compared with control group. Noradrenaline (NA) secretions were significantly increased about 15% in Dasi-Ex group, and 20~22% in Fuco-I,II,III groups compared with control group. Significant differences in brain MHPG-SO4 levels of Dasi-Ex group could not be obtained, but Fuco-I,II,III groups resulted in a marked decreases of 20~25% in brain MHPG-SO4 ratio of brain, but Fuco-I,II and III groups resulted in a marked increases of 45~60% in NA/MHPG-SO4 ratio of brain compared with control group. These results suggest that fucoidan beverage may play a effective role in a ridding of the sociopsychological stress by pivotal anti-stress effect of fucoidan.

키워드

참고문헌

  1. J. Biol. Chem. v.273 Properties of highly purified Fucan Bernardi, G.;Springer, G. F.
  2. Korean J. Gerontol v.3 no.1 Effect of wild dropwort extract on physiological activity of rats Choi, J. H.;J. I. KIM;D. W. Kim;Y. S. Moon;T. H. Yoon
  3. Korean J. Gerontol v.3 no.2 Effect of reed (Phragmites communis) root extract on physiological activity of SD rats Choi, J. H.;I. S. Kim;J. I. Kim;D. W. Kim;T. H. Yoon
  4. Korean J. Gerontol v.3 no.1 The synergistic effect of ginseng/eicosapentaenoic acid on improvement of lipid metabolism Choi, J. H.;I. S. Kim;J. I. Kim;D. W. Kim;Y. S. Moon
  5. Korean J. Gerontol v.4 no.2 Effect of aloe-added yoghurt on inhibition of obesity and biological activity of rats Choi, J. H.;J. I. Kim;D. W. Kim;Y. S. Kim;D. H. Oh
  6. Korean. J. Getrontol v.5 no.2 Effect of docosahexaenoic acid (DHA) in fish oil on experimental induced dementia, Alzheimer-type 1. Effect of DHA on lipid metabolism in rabbit Choi, J. H.;D. W. Kim;Y. S. Moon;J. I. Kim;K. S. Kim;Y. S. Kim;H. S. Yoon
  7. Korean. J. Getrontol v.5 no.2 Effect of docosahexaenoic acid (DHA) in fish oil on experimental induced dementia, Alzheimer-type 1. Effect of DHA on neurotrasmitters and their metabolites in rabbit Choi, J. H.;D. W. Kim;Y. S. Moon;J. I. Kim;K. S. Kim;Y. S. Kim;H. S. Yoon
  8. Korean. J. Getrontol v.5 no.2 Effect of docosahexaenoic acid (DHA) in fish oil on experimental induced dementia, Alzheimer-type 1. Effect of DHA on reactive oxygen species (ROS) and their scavenger enzymes in rabbits Choi, J. H.;D. W. Kim;Y. S. Moon;J. I. Kim;Y. S. Kim;H. S. Yoon
  9. korean J. Gerontol v.6 no.3 Effect of docosahexaenoic acid (DHA) on learning and memory impairment animal model SAMP8 brain III. Feeding effect of DHA on neurotrasmitters and their metabolites in SAMP8 brain Choi, J. H.;D. W. Kim;J. I. Kim;H. S. Yoon
  10. Korean J. Gerontol v.6 no.3 Effect of docosahexaenoic acid (DHA) on Learning and memory impairment animal model SAMP8 II. Feeding effect of DHA on oxygen radicals and their scavenger enzymes of SAMP8 brain Choi, J. H.;D. W. Kim;J. I. Kim;S. S. Han
  11. Korean J. Gerontol v.6 no.1 Effect of aloe (Aloe vera Linne) on learning and memory impairment animal model SAMP8 1. Effect of aloe on anti-aging action of SAMP8 Choi. J. H;D. W. Kim;J. K. Yoo;S. S. Han;S. C. S.
  12. Korean J. Life Sci. v.6 no.1 Effect of aloe (Aloe vera Linne) on learning and memory impairment animal model SAMP8 1. Effect of aloe on anti-aging action of SAMP8 II. Feeding effect of aloe on lipid metabolism of SAMP8 Choi. J. H;D. W. Kim;J. K. Yoo;S. S. Han;S. C. S.
  13. Korean J. Life Sci. v.6 no.2 Effect of aloe (Aloe vera Linne) on learning and memory impairment animal model SAMP8 1. Effect of aloe on anti-aging action of SAMP8 III. Effect of aloe on neurotransmitts and their metabolites of SAMP8 Choi. J. H;D. W. Kim;S. S. Han;S. C. S.
  14. Korean J. Gerontol v.6 no.3 Effect of docosahexaenoic acid (DHA) on learning and memory impairment animal model SAMP8 I. Feeding effect of DHA on lipid metabolism of SAMP8 brain Choi. J. H;D. W. Kim;Y. S. Han;S. S. Han
  15. J. Korean. Fish. Soc. v.30 no.4 Study on biochemical pollutant index for diagnosis of marine pollution IV. Changes in lipid components of flounder (Pleuronichthys cornutus) in the Yellow Sea Choi, J. H.;D. W. Kim;C. K. Park;J. I. Kim;D. B. Yang
  16. Korean J. gerontol v.7 no.3 Effect of red ginseng extract (REG) on learning and memory impairment animal model SAMP8. II. Feeding effect of RGE on oxygen radicals and their scavenger enzymes of SAMP8 brain Choi, J. H.;D. W. Kim;J. H. Kim;Y. S. Kim
  17. Korean J. Life Sci. v.7 no.4 Effect of pine needle extract (PNE) on physiological activity of SD rats I. Feeding effect of PNE on lipid and oxygen radical metabolisms in serum of SD rats Choi. J. H;D. W. Kim;J. H. Kim;K. S. Kim;J. S. Lee
  18. Korean J. Life Science v.7 no.1 Study on biochemical pollutant marker for diagnosis of marine pollution III. Changes in cholinesterase activity of flounder 9Paralichthys olivaceus) in the Yellow Sea Choi, J. H.;D. W. Kim;J. I. Kim;C. K. Park;D. B. Yang
  19. Korean J. Gerontol v.7 no.3 Effect of reed (Phragmites communis) root extract (RRE) on learning and memory impairment animal model SAMP8 III. Feeding effect of RRE on neurotransmitters and their metabolites in SAMP8 brain Choi, J. H.;D. W. Kim;J. S. Choi;Y. S. Han;Y. H. Baek
  20. Korean J. Gerontol v.7 no.2 Effect of red ginseng extract model SAMP8 I. Feeding effect of RGE on lipid metabolism of SAMP8 brain Choi. J. H;D. W. Kim;Y. S. Han;S. S. Han
  21. Korean J. Gerontol v.7 no.3 Effect of red ginseng extract (REG) on learning and memory impairment animal model SAMP8. III. Feeding effect of RGE on neurotransmitters and their metabolites in SAMP8 brain Choi. J. H;D. W. Kim;Y. S. Han;S. S. Han
  22. J. Korean Fish. Soc. v.30 no.4 Study on biochemical pollutant index for diagnosis of marine pollution V. Changes in oxygen radicals and their scavenger enzymes of flounder (Pleuromichthys cornutus) in the Yellow Sea Choi. J. H;D. W. Kim;Y. S. Moon;C. K. Park;D. B. Yang
  23. J. Korean Fish. Soc. v.30 no.4 Study on biochemical pollutant index for diagnosis of marine pollution VI. Changes in cholinesterase activity of flounder (Pleuronichthys cornutus) in the Yellow Sea Choi. J. H;D. W. Kim;Y. S. Moon;C. K. Park;D. B. Yang
  24. Korean J. life Science v.7 no.1 Study on biochemical pollutant index for diagnosis of marine pollution I. Changes in lipid components of flounder (Paralichthys olivaceus) in the Yellow Sea Choi. J. H;D. W. Kim;Y. S. Moon;C. K. Park;J. I. Kim;D. B. Yang
  25. Korean J. Gerontol v.7 no.3 Effect of reed (Phragmites communis) root extract (RRE) on learning and memory impairment animal model SAMP8 I. Feeding effect of RRE on lipid metabolism of SAMP8 Choi, J. H.;J. I. Kim;J. S. Lee;Y. S. Han;S. S. Han
  26. Korean J. Gerontol v.7 no.3 Effect of reed (Phragmites communis) root extract (RRE) on learning and memory impairment animal model SAMP8 II. Feeding effect of RRE on oxygen radicals and their scavenger enzymes of SAMP8 brain Choi, J. H.;J. I. Kim;K. S. Kim;C. M. Kim;Y. H. Baek
  27. Korean J. Life Science v.8 no.1 LDH/AchE and MDA/SOD ratios of flounder (Paralichthys olivaceus)as biomarkers of coastal pollution on the western coast of Korean Choi, J. H.;D. W. Kim;D. B. Yang
  28. Korean J. Life Science v.8 no.1 LDL-Choi/Hb and MDA/GSHPx ratios in serum of flounder (Pleuronichthys cornutus) as biomarker of marine pollution Choi, J. H.;D. W. Kim;D. B. Yang
  29. J. Korean Fish. Soc. v.31 no.6 Study on biochemical pollutant marker for diagnosis of marine pollution VIII. Changes in oxygen radicals and their scavenger enzymes of the flounder (Paralichthys olivaceus) in the South Sea Choi, J. H.;D. W. Kim;J. H. Kim;D. I. Kim;C. K. Park;D. B. Yang
  30. J. Korean Fish. Soc. v.31 no.6 Study on biochemical pollutant marker for diagnosis of marine pollution VII. Changes in lipid components of flounder (Paralichthys olivaceus) in the South Sea Choi, J. H.;D. W. Kim;J. H. Kim;K. S. Kim;C. K. Park;D. B. Yang
  31. Korean J. Gerontol v.8 no.1 Effect of reed root extract (RRE) on learning and memory impairment animal model SAMP8 I. Feeding effect of p-coumaric acid on lipid metabolism of SAMP8 Choi. J. H;D. W. Kim;J. S. Lee;Y. S. Han;S. S. han
  32. Korean J. Gerontol v.8 no.1 Biological activity of functional tonic beverage (FTB) using with cargasork tea Choi. J. H;D. W. Kim;Y. S. Han;H. S. Kim;C. M. Kim;W. K. Cho
  33. Korean J. Life Sci. v.8 no.2 Effect of pine needle extract (PNE) on physiological activity of SD rats. III. Feeding effect of PNE on fluidity and neurotransmitter-related enzymes in brain membranes of SD rats Choi, J. H.;J. H. Kim;D. W. Kim;C. H. Hwang;J. S. Lee
  34. Korean J. Life Sci. v.8 no.1 Effect of pine needle extract (PNE) on physiological activity of SD rats. II. Feeding effect of PNE on oxygen radicals and their scaveger enzymes in brain membranes of SD rats Choi, J. H.;J. H. Kim;D. W. Kim;K. S. Kim;J. S. Lee
  35. Korean J. Life Science v.9 no.3 Study on biochemical pollutant marker for diagnosis of marine pollution XI. Changes in cholinesterase activity of the mussel (Mytilus coruscus) in the South Sea Choi, J. H.;D. I. Kim;S. H. Park;D. W. Kim;C. K. Park;D. B. Yang
  36. Korean J. Life Science v.9 no.3 Study on biochemical pollutant marker for diagnosis of marine pollution X. Changes in oxygen radicals and their scavenger enzymes of mussel (Mytilus coruscus) in the South Sea Choi, J. H.;D. I. Kim;S. H. Park;D. W. Kim;C. K. Park;D. B. Yang
  37. Korean J. Life Sci. v.9 no.4 Effects of sea tangle (Laminaria japonica) and fucoidan components on anti-aging action Choi, J. H.;D. I. Kim;S. H. Park;D. W. Kim;J. S. Lee;J. H. Ryu;Y. S. Chung
  38. Korean J. Life Sci. v.9 no.4 Effects of sea tangle (Laminaria japonica) and fucoidan components on chronic degenerative diseases Choi, J. H.;D. I. Kim;S. H. Park;D. W. Kim;J. S. Lee;J. H. Ryu;Y. S. Chung
  39. J. Korean Fish. Soc. v.32 no.1 Study on biochemical pollutant marker for diagnosis of marine pollution IX. Changes in cholinesterase activity of the flounder (Paralichthys olivaceus) in the South Sea Choi. J. H;D. W. Kim;S. H. Park;C. K. Park;D. B. Yang
  40. Pharm. Biochem. & Behavior v.16 Physiological stress enhances noradrenaline turnover in specific brain regions in rats limori, K.;Tanaka, M.;Kohno, Y.;Ida, Y.;Nakagawa, R.;Hoaki, Y.;Tsuda, A.;Nagasawa N.
  41. Chem. Pharm. Bull. v.24 Antitumor polysaccharide fraction from Sargassum thumbergii Ito, H.;Sugiura, M.
  42. Anal. Biochem v.97 Simultaneous determination of noradrenaline and 3-methoxy-4-hydroxy-phenylethy-lene-glycol sulfate in discrete brain regions of the rat Kohno, Y.;Matsuo, K.;Tanaka, M.;Furukawa, T.;Nagasaki, N.
  43. J. Neurochem v.36 Regional distribution and production rate of 3-methoxy-4-hydroxyphenyl-ethy-leneglycol sulfate $9MHPG-SO_4$ in rat brain Kohno, Y.;Matsuo, K.;Tanaka, M.;Furukawa, T.;Nagasaki, N.
  44. J. Biol. Chem. v.193 Protein measurement with the Folin-Phenol reagent Lowry, O. H.;Roseborough, N. J.;Farr, L. A.;Randall, R. J.
  45. Korean J. Life Science v.7 no.1 Study on biochemical pollutant marker for diagnosis of marine pollution II. Changes in oxygen radicals and their scavenger enzymes of flounder (Paralichthys olivaceus) in the Yellow Sea Moon, Y. S.;D. W. Kim;J. H. Choi;C. K. Park;D. B. Yang
  46. Chemotherapy v.22 Antitumor effect of water-extracts from marine algae(I) Nakazawa, Y.;Kuroda, H.;Abe, F.;Nishino, T.;Otsuki, M.;Umezaki, I.
  47. Jpn. J. Psychosom. Med. v.6 Psychophysiology of emmotion-communication of emotion Ogawa, N.;Kuwahara, K.
  48. Endocrinology and Metabolic Clinics v.16 no.4 Stress and Glucocorticonoids in Aging Sapolsky, R.;Armanini, M.
  49. Clin. Chem. v.4 no.4 Practical procedure for estimation of corticosterone or hydrocorticortisoe Sliber, R. H.;Busch, R. D.;Oslapas, R.
  50. Agric. Biol. Chem. v.44 Isolation of highly fucoidan from Eisenia bicyclis and its anticoagulant and antitumor activities Usui, T.;Asari, K.;Mizuno, T.
  51. J. Exp. Med. v.51 Antitumor effect of seaweeds III. Antitumor effects of an extract from Sargassum Kjellmanianum Yamamoto, I.;Nagumo, T.;Takahasi, M.;Fujihara, M.;Suzuki, Y.;Iizima, I.
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