Journal of Life Science
- Volume 9 Issue 2
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- Pages.1-4
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- 1999
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- 1229-1552(pISSN)
Identification of the Strain JM-4151 Producing Nonactin, as Radical-producing Antibiotic
- Lee, Jin-Man (Department of Herb and Food Science, Kyongbuk College of Science) ;
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Lee, Dong-Sun
;
- Hong, Soon-Duck (Corresponding author, Department of Microbiology, College fo Narural Science, Kyungpook National University, Taegu 702-701, Korea.)
- Published : 1999.10.01
Abstract
Nonactin, as a radical-producing antibiotic, was isolated from the cultural broth of the strain JM-4151. This strain was identified as Streptomyces viridochromogenes and designated S. viridochromogenes JM-4151. The antibacterial activity of nonactin against Bacillus subtilis was antagonized by the activity opf quercetin, an oxygen radical scavenger. This result suggests that oxygen radical formation might be the cause for the antibacterial activity of nonactin.