Journal of Photoscience

Korean Society of Photoscience (한국광과학회)
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Investigation of Thionin Interacting With Polynucleotides by Satellite Holes

  • Yang, Yih-Pey (Institute of Atomic and Molecular Sciences, Academia Sinica) ;
  • Kevin C. Weng (Institute of Atomic and Molecular Sciences, Academia Sinica) ;
  • Yan, Cheng-Sheng (Institute of Atomic and Molecular Sciences, Academia Sinica, Departemnt of Chemistry, National Taiwan University) ;
  • Chiang, Chien-Chih (Institute of Atomic and Molecular Sciences, Academia Sinica, Departemnt of Chemistry, National Taiwan University) ;
  • Chang, Ta-Chau (Institute of Atomic and Molecular Sciences, Academia Sinica, Departemnt of Chemistry, National Taiwan University)
  • Published : 1999.05.01
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Abstract

We have introduced the nonresonant holes in the satellite hole spectrum to examine the interaction of two tautomers of thionin to various polynucleotides, including [d(GC)7]2 , [d(AT)7]2 and calf thymus. The saturated depths of nonresonant holes are much reduced upon interacting with [d(GC)7]2 and calf thymus than with [d(AT)7]2 , implying that the binding affinity of thionin to [d(GC)7]2 and calf thymus is stronger than [d(AT)7]2 . In addition, the less perturbation on the exocyclic amino group of the amino -form of thionin upon interacting with [d(AT)7]2 suggests that a direct hydrogen bond formed between the amino group of thionin and the phosphate of nucleic acids is unlikely.

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References

  1. J. Chem. Soc. Faraday Trans. v.93 Chinang, C. C.;B. C. Hwang;J. Yu;J. Y. Cheng;C. Y. Mou;S. H. Lin;T. -C. Chang
  2. Chem. Phys. Lett. v.273 Chiang, C. C.;C. Y. Mou;T. -C. Chang
  3. Chem. Phys. Lett. v.302 Weng, K. C.;C. C. Chiang;J. Y. Cheng;S. Y. Cheng;R. I. Personov;T. -C. Chang
  4. OSA TOPS on Biomedical Optical Spectroscopy and Diagnostics v.3 Chang, T. -C.;C. C. Chiang;K. Peck;E. Sevick-Muraca(Ed.);D. Benaron(Ed.)
  5. J. Chin. Chem. Soc. v.44 Cheng, J. Y.;C. C. Chiang;Y. R. Cheng;H. S. Chen;L. J. Lin;T. -C. Chang
  6. J. Phys. Chem. B v.102 Cheng, J. Y.;S. H. Lin;T.-C. Chang
  7. J. Chem. Soc. Faraday Trans. v.94 Kuo, C. T.;C. C. Chiang;J. Yu;K. Peck;T. -C. Chang
  8. Chang, T. -C.;C. T. Kuo;C. C. Chiang;J. Y. Cheng;C. S. Yan;K. Peck
  9. J. Mol. Stru. (Theochem.) v.315 Marek, N.;S. Kunsagi-Mate;K. Szabo
  10. Eur. J. Biochem. v.54 Muller, W.;D. M. Crothers
  11. Biopolymers v.35 Tuite, E.;J. M. Kelly
  12. Chem. Phys. Lett. v.223 Chang, T. -C.;Chiang, C. C.;Small, G. J.;Chou, S. H.