YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
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Syntheses of Novel 10-Oxodaunomycinone Derivatives

새로운 10-옥소다우노마이시논 유도체의 합성

  • 노영쇠 (전북대학교 자연과학대학 화학과) ;
  • 김선자 (전북대학교 자연과학대학 화학과) ;
  • 조인호 (전북대학교 자연과학대학 화학과) ;
  • 신홍식 (전북대학교 자연과학대학 화학과)
  • Published : 1999.02.01
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Abstract

A brief route for regiospecific synthesis of novel 10-Oxodaunomycinone Derivatives (10a, b) is described. Dimethoxy-l-tetralone 4 was converted to acetyl tetralone (5a, b) which was oxidized with oxygen to obtain cis-diol compound (8a, b). The construction of (10a, b) was completed by the condensation of phthaloyl dichloride 9 with cis-diol (8a, b)

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References

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