Archives of Pharmacal Research
- Volume 22 Issue 4
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- Pages.391-397
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- 1999
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- 0253-6269(pISSN)
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- 1976-3786(eISSN)
Synthesis and In Vitro Antibacterial Activity of C-3' Pyridinium Cephalosporin Derivatives
- Chung, In-Hwa (Biochemicals Research Center, Korea Institute of Science and Technology/Korea University) ;
- Kim, Choong-Sup (Biochemicals Research Center, Korea Institute of Science and Technology/Korea Research Institute of Chemical Technology) ;
- Seo, Jae-Hong (Biochemicals Research Center, Korea Institute of Science and Technology) ;
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Chung, Bong-Young
(Korea University)
- Published : 1999.08.01
Abstract
The quaternary ammonium cephalosporin derivatives were prepared with various pyridines substituted at the 3 or/and 4 position. Their in vitro antibacterial activities were determined and substituent effect on pyridine nucleus was studied. Preparation of substituted pyridines are also described.